SCHEMBL4644567

SCHEMBL4644567

CCOC(=O)/C=C/C(=O)OCC(=O)OC(=O)CCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.56
TDP1 Q9NUW8 1/20 0.50
LMNA P02545 2/20 0.49
MDM2 Q00987 2/20 0.49
MDM4 O15151 1/20 0.49
HCAR2 Q8TDS4 2/20 0.48
ABCB1 P08183 1/20 0.47
CYP4F2 P78329 1/20 0.46
CYP4A11 Q02928 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4647030 1.00 MAPT (0.56) MAPTTDP1LMNAMDM2MDM4
SCHEMBL4644575 1.00 MAPT (0.56) MAPTTDP1LMNAMDM2MDM4
SCHEMBL4643588 0.89 HCAR2 (0.55) MAPTTDP1LMNAMDM2MDM4
SCHEMBL4643598 0.89 HCAR2 (0.55) MAPTTDP1LMNAMDM2MDM4
SCHEMBL4647600 0.89 HCAR2 (0.55) MAPTTDP1LMNAMDM2MDM4
SCHEMBL4647213 0.86 MAPT (0.59) MAPTLMNAMDM2MDM4HCAR2
SCHEMBL4645341 0.86 MAPT (0.59) MAPTLMNAMDM2MDM4HCAR2
SCHEMBL4645353 0.86 MAPT (0.59) MAPTLMNAMDM2MDM4HCAR2
SCHEMBL4643581 0.82 MAPT (0.46) MAPTTDP1LMNAMDM2MDM4
SCHEMBL4647594 0.82 MAPT (0.46) MAPTTDP1LMNAMDM2MDM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed