SCHEMBL4647213

SCHEMBL4647213

CCOC(=O)/C=C\C(=O)OCC(=O)OC(=O)Cc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.59
LMNA P02545 3/20 0.51
MDM2 Q00987 2/20 0.51
MDM4 O15151 1/20 0.51
PAM P19021 1/20 0.47
KMT2A Q03164 1/20 0.46
HCAR2 Q8TDS4 3/20 0.45
ALDH1A1 P00352 3/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
MAPK1 P28482 1/20 0.45
THRB P10828 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4645341 1.00 MAPT (0.59) MAPTLMNAMDM2MDM4PAM
SCHEMBL4645353 1.00 MAPT (0.59) MAPTLMNAMDM2MDM4PAM
SCHEMBL4647774 0.89 MAPT (0.49) MAPTLMNAMDM2MDM4PAM
SCHEMBL4645084 0.89 MAPT (0.49) MAPTLMNAMDM2MDM4PAM
SCHEMBL4645073 0.89 MAPT (0.49) MAPTLMNAMDM2MDM4PAM
SCHEMBL4644575 0.86 MAPT (0.56) MAPTLMNAMDM2MDM4HCAR2
SCHEMBL4643876 0.86 MAPT (0.50) MAPTLMNAMDM2MDM4PAM
SCHEMBL4645348 0.86 MAPT (0.50) MAPTLMNAMDM2MDM4PAM
SCHEMBL4647030 0.86 MAPT (0.56) MAPTLMNAMDM2MDM4HCAR2
SCHEMBL4644567 0.86 MAPT (0.56) MAPTLMNAMDM2MDM4HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed