SCHEMBL4644592

SCHEMBL4644592

CCCCCC[Si](CCCCCC)(CCCCCC)OC(=O)CCCCCl

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.47
DGKA P23743 1/20 0.46
TSHR P16473 4/20 0.43
ALDH1A1 P00352 4/20 0.43
LMNA P02545 3/20 0.43
PAM P19021 2/20 0.42
MAPT P10636 2/20 0.41
MAPK1 P28482 1/20 0.41
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
DNM1 Q05193 1/20 0.39
NAAA Q02083 1/20 0.39
SLC22A6 Q4U2R8 1/20 0.38
SLC22A8 Q8TCC7 1/20 0.38
GPR84 Q9NQS5 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4643921 1.00 FAAH (0.47) FAAHDGKATSHRALDH1A1LMNA
SCHEMBL4641577 0.98 FAAH (0.45) FAAHDGKATSHRALDH1A1LMNA
SCHEMBL4643999 0.95 FAAH (0.45) FAAHDGKATSHRALDH1A1LMNA
SCHEMBL4644987 0.95 FAAH (0.45) FAAHDGKATSHRALDH1A1LMNA
SCHEMBL4642334 0.93 FAAH (0.42) FAAHDGKATSHRALDH1A1LMNA
SCHEMBL4641720 0.93 FAAH (0.42) FAAHDGKATSHRALDH1A1LMNA
SCHEMBL4644124 0.90 FAAH (0.43) FAAHDGKATSHRALDH1A1LMNA
SCHEMBL4642414 0.90 FAAH (0.43) FAAHDGKATSHRALDH1A1LMNA
SCHEMBL4645878 0.88 FAAH (0.41) FAAHDGKATSHRALDH1A1LMNA
SCHEMBL4642288 0.88 FAAH (0.40) FAAHDGKATSHRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed