⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL282939 | 0.69 | — | — | |
| SCHEMBL4643128 | 0.67 | — | — | |
| SCHEMBL15647982 | 0.65 | — | — | |
| SCHEMBL1864393 | 0.65 | — | — | |
| SCHEMBL2744703 | 0.62 | — | — | |
| SCHEMBL6646505 | 0.58 | — | — | |
| SCHEMBL12209468 | 0.55 | — | — | |
| SCHEMBL14303643 | 0.55 | — | — | |
| SCHEMBL7144585 | 0.55 | — | — | |
| SCHEMBL844526 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748043-B1 | Polysubstituted 1,1-pyridinyloxycyclopropanamine derivatives, process for their préparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2008-08-20 | — | — | EP | disclosed |
| EP-1748043-A1 | Polysubstituted 1,1-pyridinyloxycyclopropanamine derivatives, process for their préparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2007-01-31 | — | — | EP | disclosed |