Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1D | O15297 | 2/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4606908 | 1.00 | PPM1D (0.33) | PPM1DBUB1MEN1KMT2A | |
| SCHEMBL4606548 | 1.00 | PPM1D (0.33) | PPM1DBUB1MEN1KMT2A | |
| SCHEMBL8536413 | 0.88 | BUB1 (0.34) | PPM1DBUB1 | |
| SCHEMBL9281239 | 0.88 | BUB1 (0.34) | PPM1DBUB1 | |
| SCHEMBL3179253 | 0.88 | BUB1 (0.34) | PPM1DBUB1 | |
| SCHEMBL1799927 | 0.84 | BUB1 (0.36) | BUB1 | |
| SCHEMBL12397941 | 0.81 | BUB1 (0.32) | BUB1 | |
| SCHEMBL13236680 | 0.81 | BUB1 (0.32) | BUB1 | |
| SCHEMBL18378218 | 0.80 | BUB1 (0.32) | BUB1 | |
| SCHEMBL4644953 | 0.79 | PPM1D (0.34) | PPM1DBUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1234884-B1 | A process for the preparation of beta-hydroxy-delta-lactone using novel intermediates | COUNCIL SCIENT IND RES (IN) | 2008-08-20 | — | — | EP | claimed |
| EP-1234884-A1 | A process for the preparation of beta-hydroxy-delta-lactone using novel intermediates | Council of Scientific & Industrial Research (IN) | 2002-08-28 | — | — | EP | claimed |
| US-6388097-B1 | USING 3-HYDROXY-5-(TERT-BUTYLDIMETHYLSILYLOXY) CYCLOHEXYLACETATE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2002-05-14 | — | — | US | claimed |
| EP-1234884-B1 | A process for the preparation of beta-hydroxy-delta-lactone using novel intermediates | COUNCIL SCIENT IND RES (IN) | 2008-08-20 | — | — | EP | disclosed |
| EP-1234884-A1 | A process for the preparation of beta-hydroxy-delta-lactone using novel intermediates | Council of Scientific & Industrial Research (IN) | 2002-08-28 | — | — | EP | disclosed |
| US-6388097-B1 | USING 3-HYDROXY-5-(TERT-BUTYLDIMETHYLSILYLOXY) CYCLOHEXYLACETATE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2002-05-14 | — | — | US | disclosed |