Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.63 |
| ▸ | LMNA | P02545 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | PGR | P06401 | 3/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.63 |
| ▸ | ATM | Q13315 | 2/20 | 0.63 |
| ▸ | AR | P10275 | 1/20 | 0.63 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.63 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1656677 | 1.00 | ESR1 (0.63) | ESR1LMNASMN1; SMN2PGRSLC6A3 | |
| SCHEMBL9597951 | 0.89 | ESR1 (0.62) | ESR1LMNASMN1; SMN2PGRSLC6A3 | |
| SCHEMBL27047199 | 0.89 | LMNA (0.64) | ESR1LMNASMN1; SMN2PGRSLC6A3 | |
| SCHEMBL17775795 | 0.86 | LMNA (0.70) | ESR1LMNASMN1; SMN2PGRSLC6A3 | |
| SCHEMBL14154431 | 0.85 | ESR1 (0.67) | ESR1LMNASMN1; SMN2PGRSLC6A3 | |
| SCHEMBL27047210 | 0.85 | LMNA (0.69) | ESR1LMNASMN1; SMN2PGRSLC6A3 | |
| SCHEMBL11688794 | 0.85 | ESR1 (0.70) | ESR1LMNAPGRSLC6A3ADORA3 | |
| SCHEMBL7166132 | 0.84 | STS (0.73) | ESR1PGRSLC6A3ADORA3AR | |
| SCHEMBL4572560 | 0.84 | STS (0.73) | ESR1PGRSLC6A3ADORA3AR | |
| SCHEMBL1656550 | 0.84 | STS (0.73) | ESR1PGRSLC6A3ADORA3AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1310509-B1 | Novel anti-estrogenic steroids, and associated pharmaceutical compositions and methods of use | STANFORD RES INST INT (US) | 2008-08-13 | — | — | EP | disclosed |