SCHEMBL4645844

SCHEMBL4645844

CCOC(=O)/C=C/C(=O)OCCCC(=O)OC(=O)COC

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.47
HCAR2 Q8TDS4 5/20 0.43
MAPT P10636 5/20 0.38
RAB9A P51151 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CYP1A2 P05177 1/20 0.35
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
ALDH1A1 P00352 2/20 0.34
HTT P42858 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4645853 1.00 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4647830 1.00 ATM (0.47) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4643977 0.89 ATM (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4645231 0.89 ATM (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4643968 0.89 ATM (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL28122228 0.79 CYP1A2 (0.52) RAB9ACYP1A2TSHRALDH1A1L3MBTL1
SCHEMBL22072011 0.77 ATM (0.61) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4641808 0.77 ATM (0.45) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4641815 0.77 ATM (0.45) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL4641993 0.77 ATM (0.45) ATMHCAR2MAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed