Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 4/20 | 0.53 |
| ▸ | CLPP | Q16740 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4645872 | 1.00 | L3MBTL1 (0.68) | L3MBTL1RAB9AHSD11B1ALDH1A1GAA | |
| SCHEMBL3137416 | 0.95 | L3MBTL1 (0.69) | L3MBTL1RAB9AHSD11B1ALDH1A1GAA | |
| SCHEMBL3137399 | 0.95 | L3MBTL1 (0.69) | L3MBTL1RAB9AHSD11B1ALDH1A1GAA | |
| SCHEMBL3130199 | 0.94 | L3MBTL1 (0.63) | L3MBTL1RAB9AHSD11B1ALDH1A1GAA | |
| SCHEMBL3130211 | 0.94 | L3MBTL1 (0.63) | L3MBTL1RAB9AHSD11B1ALDH1A1GAA | |
| SCHEMBL3141460 | 0.93 | L3MBTL1 (0.58) | L3MBTL1RAB9AHSD11B1ALDH1A1POLB | |
| SCHEMBL3141476 | 0.93 | L3MBTL1 (0.58) | L3MBTL1RAB9AHSD11B1ALDH1A1POLB | |
| SCHEMBL4649009 | 0.91 | L3MBTL1 (0.58) | L3MBTL1RAB9AHSD11B1ALDH1A1GAA | |
| SCHEMBL3141179 | 0.91 | L3MBTL1 (0.63) | L3MBTL1RAB9AHSD11B1ALDH1A1GAA | |
| SCHEMBL3141171 | 0.91 | L3MBTL1 (0.63) | L3MBTL1RAB9AHSD11B1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896464-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Addex Pharma SA (CH) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006129199-A1 | NOVEL HETEROCYCLIC COMPOUNDS AS POSITIVE ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMA SA (CH) | 2006-12-07 | — | — | WO | disclosed |