Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 7/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2920263 | 1.00 | REN (0.37) | RENRORCTHRBALDH1A1CYP3A4 | |
| SCHEMBL2916732 | 0.93 | REN (0.34) | RENRORCTHRBALDH1A1CYP3A4 | |
| SCHEMBL1517975 | 0.91 | REN (0.34) | RENRORCACACB | |
| SCHEMBL1518034 | 0.91 | REN (0.34) | RENRORCACACB | |
| SCHEMBL1518032 | 0.91 | REN (0.34) | RENRORCACACB | |
| SCHEMBL1517972 | 0.91 | REN (0.34) | RENRORCACACB | |
| SCHEMBL2924426 | 0.91 | REN (0.35) | RENRORCTHRBALDH1A1CYP3A4 | |
| SCHEMBL13435437 | 0.91 | REN (0.35) | RENRORCTHRBALDH1A1CYP3A4 | |
| SCHEMBL2924429 | 0.91 | REN (0.35) | RENRORCTHRBALDH1A1CYP3A4 | |
| SCHEMBL3556958 | 0.90 | REN (0.35) | RENRORCTHRBALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1958634-A2 | Substituted piperidines as inhibitors of beta-secretase, cathepsin D, plasmepsin II and/or HIV protease | Speedel Experimenta AG (CH) | 2008-08-20 | — | — | EP | disclosed |