SCHEMBL4645969

SCHEMBL4645969

Cc1cccc2c(Cl)c3ccccc3c(Cl)c12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 7/20 0.46
CYP2A6 P11509 5/20 0.46
ALDH1A1 P00352 4/20 0.44
TSHR P16473 1/20 0.39
ACHE P22303 1/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
KIF11 P52732 1/20 0.36
MAPT P10636 3/20 0.35
HSD17B10 Q99714 2/20 0.35
HPGD P15428 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
ALKBH5 Q6P6C2 1/20 0.35
FTO Q9C0B1 1/20 0.35
KDM4E B2RXH2 1/20 0.34
ESR2 Q92731 2/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6749115 0.78 CYP1A2 (0.43) CYP1A2CYP2A6ALDH1A1TSHRACHE
SCHEMBL11530157 0.76 CYP1A2 (0.50) CYP1A2CYP2A6ALDH1A1TSHRMAOA
SCHEMBL9041013 0.74 CYP1A2 (0.50) CYP1A2CYP2A6ALDH1A1TSHRMAOA
SCHEMBL29440644 0.74 MAOA (0.58) CYP1A2CYP2A6ALDH1A1TSHRMAOA
SCHEMBL147819 0.74 MAOA (0.58) CYP1A2CYP2A6ALDH1A1TSHRMAOA
SCHEMBL2343892 0.72 CYP1A2 (0.58) CYP1A2CYP2A6ALDH1A1TSHRACHE
SCHEMBL30363673 0.72 CYP1A2 (0.58) CYP1A2CYP2A6ALDH1A1TSHRACHE
SCHEMBL4644475 0.72 MAOA (0.46) CYP1A2CYP2A6ALDH1A1TSHRACHE
Phosphine SCHEMBL9058835 0.70 CYP1A2 (0.55) CYP1A2CYP2A6ALDH1A1TSHRACHE
SCHEMBL31557694 0.70 CYP1A2 (0.48) CYP1A2CYP2A6ALDH1A1TSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924116-A Preparation method and application of compound with compression color-changing property 天津理工大学 2024-04-26 CN claimed
CN-117186397-A Polymer with anthracene fluorescent groups and biphenyl groups alternately arranged and preparation method thereof 华东理工大学 2023-12-08 CN claimed
CN-116535347-A Synthesis method of AIE fluorescent molecule and application of AIE fluorescent molecule in detection of 2,4, 6-trinitrophenol 重庆师范大学 2023-08-04 CN claimed
CN-110963911-B AIE fluorescent probe for heparin detection and pH response, synthetic method and application 重庆师范大学 2022-03-22 CN claimed
CN-108069912-B Tetradentate benzoquinazoline salt compound and preparation method and application thereof 天津师范大学 2020-11-10 CN claimed
EP-4091578-B1 METHOD FOR PRODUCING PLATE DENTURE TOKUYAMA DENTAL CORP (JP) 2024-10-09 EP disclosed
CN-117924116-A Preparation method and application of compound with compression color-changing property 天津理工大学 2024-04-26 CN disclosed
US-11857385-B2 Method of producing plate denture, curable composition for stereolithography, and plate denture production kit TOKUYAMA DENTAL CORPORATION (JP) 2024-01-02 US disclosed
CN-117186397-A Polymer with anthracene fluorescent groups and biphenyl groups alternately arranged and preparation method thereof 华东理工大学 2023-12-08 CN disclosed
CN-116535347-A Synthesis method of AIE fluorescent molecule and application of AIE fluorescent molecule in detection of 2,4, 6-trinitrophenol 重庆师范大学 2023-08-04 CN disclosed
CN-116535347-A Synthesis method of AIE fluorescent molecule and application of AIE fluorescent molecule in detection of 2,4, 6-trinitrophenol 重庆师范大学 2023-08-04 CN disclosed
US-20230137898-A1 METHOD OF PRODUCING PLATE DENTURE, CURABLE COMPOSITION FOR STEREOLITHOGRAPHY, AND PLATE DENTURE PRODUCTION KIT TOKUYAMA DENTAL CORPORATION (JP) 2023-05-04 US disclosed
EP-0698823-A1 Antireflective coating for microlithography International Business Machines Corporation (US) 1996-02-28 EP disclosed
EP-0579646-B1 ANTI-CANCER ANTRACENE DERIVATIVES BRITISH TECH GROUP (GB) 1995-12-27 EP disclosed
US-5461078-A Anti-cancer compounds BRITISH TECHNOLOGY GROUP LIMITED (GB) 1995-10-24 US disclosed
EP-0579646-A1 ANTI-CANCER ANTRACENE DERIVATIVES. BRITISH TECH GROUP (GB) 1994-01-26 EP disclosed
WO-1992018469-A1 ANTI-CANCER ANTRACENE DERIVATIVES BRITISH TECHNOLOGY GROUP LTD. (GB) 1992-10-29 WO disclosed
US-4178242-A Method for the purification of sewage waters which contain organic compounds of an anionic character ANIC S.P.A. (IT) 1979-12-11 US disclosed
US-4121932-A Electrophotographic process involving dye transfer imagewise MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1978-10-24 US disclosed
US-4101510-A SUBSTITUTED VINYL AROMATIC MONOMER, LEWIS ACID STANDARD OIL COMPANY A CORPORATION OF INDIANA (US) 1978-07-18 US disclosed