⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18095048 | 0.69 | — | — | |
| SCHEMBL20698420 | 0.67 | ADORA2A (0.39) | — | |
| SCHEMBL20113012 | 0.67 | — | — | |
| SCHEMBL20698663 | 0.64 | ADORA2A (0.38) | — | |
| SCHEMBL20698656 | 0.64 | ADORA2A (0.38) | — | |
| SCHEMBL4448933 | 0.64 | — | — | |
| SCHEMBL14380284 | 0.63 | ALDH1A1 (0.36) | — | |
| SCHEMBL352077 | 0.63 | HSP90AA1 (0.39) | — | |
| SCHEMBL138622 | 0.63 | ADORA2A (0.36) | — | |
| SCHEMBL31590774 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997686-B | Method for producing 2, 3-biphosphinylpyrazine derivative and method for producing phosphine transition metal complex | 日本化学工业株式会社 | 2023-11-03 | — | — | CN | claimed |
| US-11773120-B2 | Method for producing optically active 2, 3-bisphosphinopyrazine derivative and method for producing optically active phosphine transition metal complex | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2023-10-03 | — | — | US | claimed |
| CN-111032668-B | Optically active 2,3-bisphosphinylpyrazine derivative, process for producing the same, transition metal complex, and process for producing organoboron compound | 日本化学工业株式会社 | 2022-10-14 | — | — | CN | claimed |
| US-11084835-B2 | 2,3-bisphosphinopyrazine derivative, method for producing same, transition metal complex, asymmetric catalyst, and method for producing organic boron compound | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2021-08-10 | — | — | US | claimed |
| US-20210047351-A1 | 2,3-BISPHOSPHINOPYRAZINE DERIVATIVE, METHOD FOR PRODUCING SAME, TRANSITION METAL COMPLEX, ASYMMETRIC CATALYST, AND METHOD FOR PRODUCING ORGANIC BORON COMPOUND | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2021-02-18 | — | — | US | claimed |
| US-20200377536-A1 | OPTICALLY ACTIVE 2,3-BISPHOSPHINOPYRAZINE DERIVATIVE, METHOD FOR PRODUCING SAME, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCING ORGANIC BORON COMPOUND | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2020-12-03 | — | — | US | claimed |
| US-20200247833-A1 | METHOD FOR PRODUCING 2,3-BISPHOSPHINOPYRAZINE DERIVATIVE, AND METHOD FOR PRODUCING PHOSPHINE TRANSITION METAL COMPLEX | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2020-08-06 | — | — | US | claimed |
| CN-111032668-A | Optically active 2, 3-bisphosphinylpyrazine derivative, method for producing same, transition metal complex, and method for producing organoboron compound | 日本化学工业株式会社 | 2020-04-17 | — | — | CN | claimed |
| US-20200087330-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE 2, 3-BISPHOSPHINOPYRAZINE DERIVATIVE AND METHOD FOR PRODUCING OPTICALLY ACTIVE PHOSPHINE TRANSITION METAL COMPLEX | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2020-03-19 | — | — | US | claimed |
| WO-2019172150-A1 | 2,3-BISPHOSPHINOPYRAZINE DERIVATIVE, METHOD FOR PRODUCING SAME, TRANSITION METAL COMPLEX, ASYMMETRIC CATALYST, AND METHOD FOR PRODUCING ORGANIC BORON COMPOUND | 日本化学工業株式会社 | 2019-09-12 | — | — | WO | claimed |
| WO-2026023360-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE HYDROGEN-PHOSPHINE BORANE COMPOUND AND METHOD FOR PRODUCING OPTICALLY ACTIVE 2,3-BISPHOSPHINOPYRAZINE DERIVATIVE | 日本化学工業株式会社 | 2026-01-29 | — | — | WO | disclosed |
| CN-110997686-B | Method for producing 2, 3-biphosphinylpyrazine derivative and method for producing phosphine transition metal complex | 日本化学工业株式会社 | 2023-11-03 | — | — | CN | disclosed |
| US-11773120-B2 | Method for producing optically active 2, 3-bisphosphinopyrazine derivative and method for producing optically active phosphine transition metal complex | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2023-10-03 | — | — | US | disclosed |
| US-11773120-B2 | Method for producing optically active 2, 3-bisphosphinopyrazine derivative and method for producing optically active phosphine transition metal complex | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2023-10-03 | — | — | US | disclosed |
| US-11773120-B2 | Method for producing optically active 2, 3-bisphosphinopyrazine derivative and method for producing optically active phosphine transition metal complex | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2023-10-03 | — | — | US | disclosed |
| WO-2011126045-A1 | PROCESS FOR PREPARATION OF PYRAZINE DERIVATIVES | 日本化学工業株式会社 (JP) | 2011-10-13 | — | — | WO | disclosed |
| WO-2006068879-A1 | TETRADENTATE LIGANDS AND METAL COMPLEXES THEREOF FOR ASYMMETRIC CATALYSIS | EASTMAN CHEMICAL COMPANY (US) | 2006-06-29 | — | — | WO | disclosed |
| US-20060135804-A1 | Tetradentate ligands and metal complexes thereof for asymmetric catalysis | EASTMAN CHEMICAL COMPANY | 2006-06-22 | — | — | US | disclosed |
| EP-0649421-A1 | HEXADENTATE LIGANDS USEFUL IN RADIOGRAPHIC IMAGING AGENTS | MALLINCKRODT MEDICAL, INC. (US) | 1995-04-26 | — | — | EP | disclosed |
| EP-0649421-A4 | HEXADENTATE LIGANDS USEFUL IN RADIOGRAPHIC IMAGING AGENTS. | MALLINCKRODT MEDICAL INC (US) | 1995-03-13 | — | — | EP | disclosed |