Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 15/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.48 |
| ▸ | PGR | P06401 | 4/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.48 |
| ▸ | NEK1 | Q96PY6 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4646281 | 0.91 | NR3C1 (0.49) | NR3C1NR3C2PGRNEK1MEN1 | |
| SCHEMBL4649348 | 0.87 | NEK1 (0.48) | NR3C1NR3C2PGRKCNA5NEK1 | |
| SCHEMBL4648904 | 0.86 | NR3C1 (0.52) | NR3C1NR3C2PGRNEK1KMT2A | |
| SCHEMBL4648234 | 0.85 | KCNA5 (0.67) | NR3C1KCNA5MEN1KMT2A | |
| SCHEMBL4648226 | 0.85 | KCNA5 (0.67) | NR3C1KCNA5MEN1KMT2A | |
| SCHEMBL14025313 | 0.84 | NEK1 (0.47) | NR3C1NR3C2PGRKCNA5NEK1 | |
| SCHEMBL4646109 | 0.80 | NR3C1 (0.47) | NR3C1NR3C2PGRKCNA5NEK1 | |
| SCHEMBL4647445 | 0.80 | NEK1 (0.65) | NR3C1NR3C2PGRNEK1 | |
| SCHEMBL4649023 | 0.80 | NEK1 (0.55) | NR3C1NR3C2PGRNEK1 | |
| SCHEMBL3122145 | 0.80 | NR3C1 (0.64) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080255117-A1 | SULFONYLTRYPTOPHANOLS | BAYER SCHERING PHARMA AG (DE) | 2008-10-16 | — | — | US | claimed |
| US-20080255117-A1 | SULFONYLTRYPTOPHANOLS | BAYER SCHERING PHARMA AG (DE) | 2008-10-16 | — | — | US | disclosed |
| WO-2008104597-A2 | SULFONYLTRYPTOPHANOLS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-09-04 | — | — | WO | disclosed |
| EP-1964834-A1 | Sulphonyltryptophanols | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-09-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080255117-A1 | SULFONYLTRYPTOPHANOLS | FSHR, NPY1R, GNRHR | NR3C1 932/4885NR3C2 725/4885PGR 185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.