⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16685935 | 0.83 | — | — | |
| SCHEMBL22497794 | 0.81 | — | — | |
| SCHEMBL6141371 | 0.75 | — | — | |
| SCHEMBL8427780 | 0.72 | — | — | |
| SCHEMBL6893105 | 0.72 | — | — | |
| SCHEMBL7712045 | 0.71 | — | — | |
| SCHEMBL6247753 | 0.71 | — | — | |
| SCHEMBL1016480 | 0.71 | — | — | |
| SCHEMBL950247 | 0.71 | — | — | |
| Tert-Butanol SCHEMBL6429201 | 0.71 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023534-A | Cobalt compounds and methods of making and using the same | 弗萨姆材料美国有限责任公司 | 2019-07-16 | — | — | CN | claimed |
| CN-101925858-B | Polychromic substance and use thereof | DATALASE LTD | 2012-12-19 | — | — | CN | claimed |
| CN-101925858-A | Polychromic substance and use thereof | DATALASE LTD | 2010-12-22 | — | — | CN | claimed |
| US-20250304576-A1 | IKK INHIBITORS | CANCER RESEARCH TECH LTD (GB) | 2025-10-02 | — | — | US | disclosed |
| EP-4004000-B1 | THIENOPYRIDINYL AND THIAZOLOPYRIDINYL COMPOUNDS USEFUL AS IRAK4 INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2025-07-09 | — | — | EP | disclosed |
| US-12304916-B2 | Thienopyridinyl and thiazolopyridinyl compounds useful as IRAK4 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-05-20 | — | — | US | disclosed |
| CN-115335043-B | PGDH inhibitors and methods of making and using the same | 迈欧伏特治疗公司 | 2025-03-28 | — | — | CN | disclosed |
| EP-3947378-B1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS | GALAPAGOS NV (BE) | 2024-11-13 | — | — | EP | disclosed |
| US-20240262820-A1 | PGDH INHIBITORS AND METHODS OF MAKING AND USING | MYOFORTE THERAPEUTICS, INC. | 2024-08-08 | — | — | US | disclosed |
| WO-2024129763-A1 | MODULATORS OF TNF-α ACTIVITY | FORWARD THERAPEUTICS, INC. (US) | 2024-06-20 | — | — | WO | disclosed |
| CN-118125978-A | MYC inhibitor and preparation method and application thereof | 安徽中医药大学 | 2024-06-04 | — | — | CN | disclosed |
| US-20080293782-A1 | 1,1,3-Trioxo-1,2,5-Thiadiazolidines and Their Use as Ptp-Ases Inhibitors | NOVARTIS AG (CH) | 2008-11-27 | — | — | US | disclosed |
| EP-1960377-A1 | l , l , 3-TRI0X0-l , 2 , 5-THIADIAZ0LIDINES AND THEIR USE AS PTP-ASES INHIBITORS | Novartis AG (CH) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007067614-A1 | l, l, 3-TRI0X0-l, 2, 5-THIADIAZ0LIDINES AND THEIR USE AS PTP-ASES INHIBITORS | NOVARTIS AG (CH) | 2007-06-14 | — | — | WO | disclosed |
| WO-2005044008-A2 | 2 -AMINOTHIOPHENE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-05-19 | — | — | WO | disclosed |
| US-6013814-A | Vitamin D analogues | RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY, INC. (US) | 2000-01-11 | — | — | US | disclosed |
| US-5872140-A | Vitamin D analogues | RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY, INC. (US) | 1999-02-16 | — | — | US | disclosed |
| EP-0710227-B1 | VITAMIN D ANALOGUES | RES INST MEDICINE CHEM (US) | 1998-10-21 | — | — | EP | disclosed |
| EP-0710227-A1 | VITAMIN D ANALOGUES | RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY INC. (US) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995003273-A1 | VITAMIN D ANALOGUES | HOLMES, MICHAEL, JOHN (GB) | 1995-02-02 | — | — | WO | disclosed |