SCHEMBL4646986

SCHEMBL4646986

O=C(CCO)Oc1c(Cl)cc(Br)cc1Br

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 1/20 0.36
HSD17B10 Q99714 1/20 0.36
KDM4E B2RXH2 4/20 0.35
POLB P06746 1/20 0.35
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MCHR1 Q99705 1/20 0.32
ALOX15 P16050 1/20 0.32
TPMT P51580 1/20 0.32
RECQL P46063 1/20 0.31
THRB P10828 1/20 0.31
NPY1R P25929 1/20 0.31
NPY2R P49146 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4641988 0.92 VCAM1 (0.38) VCAM1KDM4EPOLBMEN1KMT2A
SCHEMBL4645070 0.91 VCAM1 (0.39) VCAM1HSD17B10KDM4EPOLBMEN1
SCHEMBL4642068 0.89 VCAM1 (0.40) VCAM1HSD17B10KDM4EPOLBMEN1
SCHEMBL4646760 0.88 HSD17B10 (0.41) VCAM1HSD17B10MEN1KMT2ATDP1
SCHEMBL4644450 0.87 HSD17B10 (0.36) HSD17B10KDM4EPOLBMEN1KMT2A
SCHEMBL4641402 0.87 HSD17B10 (0.38) VCAM1HSD17B10KDM4EPOLBMEN1
SCHEMBL4642291 0.86 HSD17B10 (0.35) HSD17B10KDM4EPOLBMEN1KMT2A
SCHEMBL4643853 0.84 KDM4E (0.39) HSD17B10KDM4EPOLBMEN1KMT2A
SCHEMBL4644473 0.83 HSD17B10 (0.38) HSD17B10KDM4EPOLBMEN1KMT2A
SCHEMBL4645432 0.83 KDM4E (0.39) HSD17B10KDM4EPOLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed