Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.44 |
| ▸ | FPR2 | P25090 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | REN | P00797 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22679471 | 0.87 | HDAC4 (0.57) | HDAC4HDAC1HDAC6AAK1FPR2 | |
| SCHEMBL8121031 | 0.83 | KMT2A (0.46) | HDAC4HDAC1HDAC6GAAEPHX1 | |
| SCHEMBL8121033 | 0.83 | KMT2A (0.46) | HDAC4HDAC1HDAC6GAAEPHX1 | |
| SCHEMBL8387090 | 0.83 | KMT2A (0.46) | HDAC4HDAC1HDAC6GAAEPHX1 | |
| SCHEMBL2724209 | 0.82 | AAK1 (0.42) | HDAC4HDAC1HDAC6AAK1GAA | |
| SCHEMBL3039995 | 0.80 | AAK1 (0.50) | HDAC4HDAC1HDAC6AAK1GAA | |
| SCHEMBL31311637 | 0.80 | AAK1 (0.50) | HDAC4HDAC1HDAC6AAK1GAA | |
| SCHEMBL3039988 | 0.80 | AAK1 (0.50) | HDAC4HDAC1HDAC6AAK1GAA | |
| SCHEMBL25306007 | 0.79 | BTK (0.50) | GAAEPHX1CTSKBTKREN | |
| SCHEMBL48274 | 0.79 | BTK (0.50) | GAAEPHX1CTSKBTKREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685102-A4 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD (KR) | 2008-08-20 | — | — | EP | disclosed |
| EP-1685102-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG Life Sciences Ltd. (KR) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005047251-A1 | MELANOCORTIN RECEPTOR AGONISTS | LG LIFE SCIENCES LTD. (KR) | 2005-05-26 | — | — | WO | disclosed |