Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.44 |
| ▸ | MDM4 | O15151 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.41 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4644561 | 1.00 | MAPT (0.48) | MAPTLMNAMDM2MDM4MMP8 | |
| SCHEMBL4643584 | 0.81 | MAPT (0.45) | MAPTLMNAMDM2MDM4MMP8 | |
| SCHEMBL4647597 | 0.81 | MAPT (0.45) | MAPTLMNAMDM2MDM4MMP8 | |
| SCHEMBL4644572 | 0.80 | MAPT (0.46) | MAPTLMNAMDM2MDM4HCAR2 | |
| SCHEMBL4647206 | 0.79 | MAPT (0.52) | MAPTLMNAMDM2MDM4MMP8 | |
| SCHEMBL4645338 | 0.79 | MAPT (0.52) | MAPTLMNAMDM2MDM4MMP8 | |
| SCHEMBL4642725 | 0.79 | MAPT (0.50) | MAPTLMNAMDM2MDM4HCAR2 | |
| SCHEMBL4646779 | 0.79 | MAPT (0.50) | MAPTLMNAMDM2MDM4HCAR2 | |
| SCHEMBL11436318 | 0.78 | MMP8 (0.54) | MMP8ALDH1A1PPARGPPARASRR | |
| SCHEMBL4645346 | 0.77 | MAPT (0.46) | MAPTLMNAMDM2MDM4HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487928-B1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2008-08-13 | — | — | EP | disclosed |