SCHEMBL464717

SCHEMBL464717

CC(C)(C)OOC(C)(CCC(C)(OOC(C)(C)C)c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.48
ALDH1A1 P00352 3/20 0.40
TAAR1 Q96RJ0 2/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
HSD17B10 Q99714 1/20 0.38
KCNN4 O15554 3/20 0.38
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
SLC6A2 P23975 1/20 0.35
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
CYP3A4 P08684 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
KIF11 P52732 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7628903 0.83 MAPK1 (0.45) MAPK1ALDH1A1TAAR1ALOX15TSHR
SCHEMBL746390 0.82 MAPK1 (0.43) MAPK1ALDH1A1TAAR1ALOX15TSHR
SCHEMBL481584 0.80 MAPK1 (0.42) MAPK1ALDH1A1TAAR1ALOX15TSHR
SCHEMBL17825586 0.77 MAPK1 (0.39) MAPK1ALDH1A1TAAR1ALOX15TSHR
SCHEMBL11208770 0.77 MAPK1 (0.52) MAPK1ALDH1A1TAAR1ALOX15TSHR
SCHEMBL1581356 0.76 MAPK1 (0.42) MAPK1SLC6A2ESR1
SCHEMBL1581716 0.76 MAPK1 (0.42) MAPK1SLC6A2ESR1
SCHEMBL22351 0.76 MAPK1 (0.50) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL9861248 0.75 MAPK1 (0.45) MAPK1ALDH1A1TAAR1ALOX15TSHR
SCHEMBL29737415 0.75 MAPK1 (0.37) MAPK1ALDH1A1TAAR1ALOX15KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1554337-B2 SCRATCH AND MAR RESISTANT SOFT ETHYLENE ELASTOMER COMPOSITIONS DU PONT (US) 2011-11-30 EP claimed
JP-4769576-B2 2011-09-07 JP claimed
EP-0963406-B1 RHEOLOGY-MODIFIED THERMOPLASTIC ELASTOMER COMPOSITIONS AND ARTICLES FABRICATED THEREFROM DOW GLOBAL TECHNOLOGIES INC (US) 2010-09-08 EP claimed
EP-1546247-B1 RHEOLOGY-MODIFIED THERMOPLASTIC ELASTOMER COMPOSITIONS FOR EXTRUDED PROFILES DOW GLOBAL TECHNOLOGIES INC (US) 2008-07-23 EP claimed
US-7338994-B2 Rheology-modified thermoplastic elastomer compositions for extruded profiles DOW GLOBAL TECHNOLOGIES INC. (US) 2008-03-04 US claimed
US-20070004864-A1 Method to enhance impact strength properties of melt processed polypropylene resins UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) 2007-01-04 US claimed
EP-1554337-B1 SCRATCH AND MAR RESISTANT SOFT ETHYLENE ELASTOMER COMPOSITIONS DU PONT (US) 2006-11-29 EP claimed
EP-1319041-B1 THERMOPLASTIC ELASTOMER COMPOSITIONS RHEOLOGY-MODIFIED USING PEROXIDES AND FREE RADICAL COAGENTS DUPONT DOW ELASTOMERS LLC (US) 2006-03-01 EP claimed
JP-2006503970-A 2006-02-02 JP claimed
EP-1554337-A2 SCRATCH AND MAR RESISTANT SOFT ETHYLENE ELASTOMER COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2005-07-20 EP claimed
WO-2004037916-A2 SCRATCH AND MAR RESISTANT SOFT ETHYLENE ELASTOMER COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-05-06 WO claimed
WO-2004031284-A1 RHEOLOGY-MODIFIED THERMOPLASTIC ELASTOMER COMPOSITIONS FOR EXTRUDED PROFILES DUPONT DOW ELASTOMERS L.L.C. (US) 2004-04-15 WO claimed
US-20030158341-A1 Thermoplastic elastomer compositions rheology-moified using peroxides and free radical coagents DOW GLOBAL TECHNOLOGIES LLC 2003-08-21 US claimed
EP-1319041-A1 THERMOPLASTIC ELASTOMER COMPOSITIONS RHEOLOGY-MODIFIED USING PEROXIDES AND FREE RADICAL COAGENTS DUPONT DOW ELASTOMERS L.L.C. (US) 2003-06-18 EP claimed
US-6548600-B2 Elastomeric ethylene/alpha-olefin (EAO) polymer or EAO polymer blend and a high melting propylene polymer; rheology modification is induced by a combination of a peroxide and a free radical coagent DUPONT DOW ELASTOMERS L.L.C. 2003-04-15 US claimed
US-6506842-B1 Gel-free blend of propylene polymer and ethylene-alpha-olefin copolymer modified by free radical generator, heat, or radiation DUPONT DOW ELASTOMERS L.L.C. 2003-01-14 US claimed
US-20020115796-A1 Thermoplastic elastomer compositions rheology-modified using peroxides and free radical coagents DOW GLOBAL TECHNOLOGIES LLC 2002-08-22 US claimed
WO-2002024803-A1 THERMOPLASTIC ELASTOMER COMPOSITIONS RHEOLOGY-MODIFIED USING PEROXIDES AND FREE RADICAL COAGENTS DUPONT DOW ELASTOMERS L.L.C. (US) 2002-03-28 WO claimed
EP-0963406-A1 RHEOLOGY-MODIFIED THERMOPLASTIC ELASTOMER COMPOSITIONS AND ARTICLES FABRICATED THEREFROM DUPONT DOW ELASTOMERS L.L.C. (US) 1999-12-15 EP claimed
WO-1998032795-A1 RHEOLOGY-MODIFIED THERMOPLATIC ELASTOMER COMPOSITIONS AND ARTICLES FABRICATED THEREFROM DUPONT DOW ELASTOMERS L.L.C. (US) 1998-07-30 WO claimed