SCHEMBL11208770

SCHEMBL11208770

CCC(C)(OOC(C)(CC)c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.52
ALDH1A1 P00352 3/20 0.43
TAAR1 Q96RJ0 2/20 0.43
ALOX15 P16050 1/20 0.43
KCNN4 O15554 3/20 0.41
TSHR P16473 1/20 0.40
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
SLC6A2 P23975 1/20 0.38
ESR1 P03372 2/20 0.37
ESR2 Q92731 2/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.35
KMT2A Q03164 1/20 0.35
NR3C2 P08235 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27338347 0.92 MAPK1 (0.45) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL27338474 0.92 MAPK1 (0.45) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL14389655 0.92 MAPK1 (0.68) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL27338478 0.92 MAPK1 (0.45) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL7448596 0.86 MAPK1 (0.46) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL1774346 0.84 MAPK1 (0.44) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL8679355 0.83 MAPK1 (0.45) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL297402 0.82 ALDH1A1 (0.56) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL5387344 0.82 MAPK1 (0.43) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL24856246 0.81 CYP2C19 (0.42) MAPK1ALDH1A1ALOX15KCNN4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0021665-B1 PROCESS FOR PRODUCING ARALKYL ALCOHOLS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1983-02-09 EP disclosed
US-4322567-A BY HYDROGENATION OF A TETRIARY PEROXIDE MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) 1982-03-30 US disclosed
US-4316967-A EPOXIDIZED VINYL POLYMERS ENDCAPPED WITH POLYISOLYANATES OR POLYISOTHIOCYANTES THE FIRESTONE TIRE & RUBBER COMPANY (US) 1982-02-23 US disclosed
US-4299932-A ADDITION-CONDENSATION COPOLYMER OF A HYDROLYSED ISOCYANATE-AMIDE-MODIFIED DIENE, POLYURETHANE, AND POLYUREA THE FIRESTONE TIRE & RUBBER COMPANY (US) 1981-11-10 US disclosed
US-4298707-A ADDITION-CONDENSATION POLYMER FOAMS THE FIRESTONE TIRE & RUBBER COMPANY (US) 1981-11-03 US disclosed
EP-0021665-A1 Process for producing aralkyl alcohols MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1981-01-07 EP disclosed
US-4239860-A REACTING AMINE-TERMINATED ADDITION POLYMER WITH POLYURETHANE THE FIRESTONE TIRE & RUBBER COMPANY (US) 1980-12-16 US disclosed
US-4235979-A Amine terminated polymers and the formation of block copolymers THE FIRESTONE TIRE & RUBBER COMPANY (US) 1980-11-25 US disclosed
EP-0002196-A1 Amine terminated block copolymers and processes for their preparation THE FIRESTONE TIRE & RUBBER COMPANY (US) 1979-06-13 EP disclosed
US-4157429-A Amine terminated polymers and the formation of block copolymers THE FIRESTONE TIRE & RUBBER COMPANY (US) 1979-06-05 US disclosed
US-4157430-A Amine terminated polymers and the formation of block copolymers THE FIRESTONE TIRE & RUBBER COMPANY (US) 1979-06-05 US disclosed
US-4155947-A Amine terminated polymers and the formation of blocked copolymers THE FIRESTONE TIRE & RUBBER COMPANY (US) 1979-05-22 US disclosed
US-4155948-A Amine terminated polymers and the formation of blocked copolymers THE FIRESTONE TIRE & RUBBER COMPANY (US) 1979-05-22 US disclosed
US-4154913-A ADDITION POLYMER ENDCAPPED WITH POLYISOCYANATE THE FIRESTONE TIRE & RUBBER COMPANY (US) 1979-05-15 US disclosed
US-4154772-A PHENOLIC RESIN CONNECTED TO ADDITION POLYMER THE FIRESTONE TIRE & RUBBER COMPANY (US) 1979-05-15 US disclosed
US-4154773-A UREA-ALDEHYDE POLYMER COUPLED TO ADDITION POLYMER THE FIRESTONE TIRE & RUBBER COMPANY (US) 1979-05-15 US disclosed
US-4151222-A Amine terminated polymers and the formation of block copolymers THE FIRESTONE TIRE & RUBBER COMPANY (US) 1979-04-24 US disclosed
US-4070344-A WITH POLYISOCYANATE, AMIDE, HYDROLYSIS THE FIRESTONE TIRE AND RUBBER COMPANY (US) 1978-01-24 US disclosed