Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ING2 | Q9H160 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NT5E | P21589 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3136473 | 0.85 | LCK (0.44) | ING2LCKFYNTSHRTDP1 | |
| SCHEMBL3140914 | 0.85 | CYP3A4 (0.43) | ING2TSHRCYP3A4TDP1CA1 | |
| SCHEMBL9635604 | 0.83 | CYP3A4 (0.42) | ING2TSHRCYP3A4TDP1CA1 | |
| SCHEMBL197184 | 0.74 | LCK (0.46) | ING2LCKFYNTSHRCYP3A4 | |
| SCHEMBL11522707 | 0.72 | NMT1 (0.41) | TSHRCYP3A4TDP1CA1CA2 | |
| SCHEMBL11871290 | 0.72 | FABP3 (0.35) | LCKFYNCA1CA2CA3 | |
| SCHEMBL11078671 | 0.72 | LCK (0.44) | ING2LCKFYNTSHRCYP3A4 | |
| SCHEMBL31357033 | 0.71 | CYP3A4 (0.39) | TSHRCYP3A4TDP1CA1CA2 | |
| SCHEMBL1041550 | 0.70 | ING2 (0.52) | ING2LCKFYNTSHRCYP3A4 | |
| SCHEMBL27468675 | 0.69 | LCK (0.39) | ING2LCKFYNTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443042-B1 | HYBRID ONIUM SALT | WAKO PURE CHEM IND LTD (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-7101918-B2 | Hybrid type onium salt | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2006-09-05 | — | — | US | disclosed |
| US-20050020710-A1 | Hybrid onium salt | WAKO PURE CHEMICALS INDUSTRIES, LTD. (JP) | 2005-01-27 | — | — | US | disclosed |
| EP-1443042-A1 | HYBRID ONIUM SALT | Wako Pure Chemical Industries, Ltd. (JP) | 2004-08-04 | — | — | EP | disclosed |