Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | NT5E | P21589 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 3/20 | 0.32 |
| ▸ | ACP1 | P24666 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.31 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27481037 | 0.84 | LCK (0.46) | LCKFYNING2TSHRSMN1; SMN2 | |
| SCHEMBL197184 | 0.84 | LCK (0.46) | LCKFYNING2TSHRSMN1; SMN2 | |
| SCHEMBL198861 | 0.84 | LCK (0.46) | LCKFYNING2TSHRSMN1; SMN2 | |
| SCHEMBL11078671 | 0.81 | LCK (0.44) | LCKFYNING2TSHRSMN1; SMN2 | |
| SCHEMBL4452071 | 0.77 | LCK (0.41) | LCKFYNING2TSHRSMN1; SMN2 | |
| SCHEMBL17262659 | 0.76 | LMNA (0.44) | LCKFYNING2TSHRSMN1; SMN2 | |
| SCHEMBL17262653 | 0.76 | LMNA (0.44) | LCKFYNING2TSHRSMN1; SMN2 | |
| SCHEMBL17262651 | 0.74 | ALDH1A1 (0.50) | LCKFYNING2TSHRSMN1; SMN2 | |
| SCHEMBL1510131 | 0.74 | LCK (0.39) | LCKFYNING2TSHRSMN1; SMN2 | |
| SCHEMBL17262657 | 0.74 | ALDH1A1 (0.50) | LCKFYNING2TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1131153-A | 1-oxy-2-(phenylsulfonamido-) amyl piperidine derivant, its preparation method and medicinal use thereof | SYNTHELABO (FR) | 1996-09-18 | — | — | CN | disclosed |