SCHEMBL4647397

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4648263	0.86	CHRM2 (0.43)	ALDH1A1HTTKDM4ESMN1; SMN2HSD11B1
	SCHEMBL602399	0.86	CHRM2 (0.51)	ALDH1A1HSD11B1CHRM2CHRM4CHRM5
	SCHEMBL8241634	0.84	CCR4 (0.48)	ALDH1A1HTTKDM4ESMN1; SMN2HSD11B1
	Hydrochloric Acid SCHEMBL4648276	0.82	CCR4 (0.48)	ALDH1A1HTTKDM4ESMN1; SMN2HSD11B1
	SCHEMBL4649346	0.82	OPRM1 (0.49)	CHRM2CHRM4CHRM5CHRM1CHRM3
	SCHEMBL4647304	0.82	CHRM2 (0.47)	HSD11B1CHRM2CHRM4CHRM5CHRM1
	SCHEMBL4647996	0.82	CHRM1 (0.65)	HSD11B1CHRM2CHRM4CHRM5CHRM1
	Hydrochloric Acid SCHEMBL4749717	0.81	OPRM1 (0.48)	CHRM2CHRM4CHRM5CHRM1CHRM3
	Hydrochloric Acid SCHEMBL4749245	0.81	CHRM1 (0.64)	HSD11B1CHRM2CHRM4CHRM5CHRM1
	SCHEMBL4906414	0.80	CHRM1 (0.73)	ALDH1A1HTTKDM4ESMN1; SMN2HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.