SCHEMBL4647529

SCHEMBL4647529

O=Cc1cccc(OC(=O)CCl)c1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.54
KMT2A Q03164 4/20 0.54
RAB9A P51151 3/20 0.54
GAA P10253 1/20 0.54
MAPT P10636 1/20 0.54
HPGD P15428 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
SRC P12931 1/20 0.50
POLB P06746 2/20 0.49
MEN1 O00255 2/20 0.49
BLM P54132 1/20 0.49
MCL1 Q07820 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
ALDH1A1 P00352 1/20 0.49
MAOA P21397 7/20 0.47
MAOB P27338 7/20 0.47
UNG P13051 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ACHE P22303 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4644755 0.87 NPC1 (0.51) NPC1KMT2ARAB9AGAAMAPT
SCHEMBL4644532 0.85 SRC (0.51) NPC1KMT2ARAB9AGAAMAPT
SCHEMBL4642467 0.84 KMT2A (0.54) NPC1KMT2ARAB9AGAAMAPT
SCHEMBL4641696 0.83 NPC1 (0.52) NPC1KMT2ARAB9AGAAMAPT
SCHEMBL29042154 0.83 KMT2A (0.50) NPC1KMT2ARAB9AGAAMAPT
SCHEMBL1244858 0.83 ACHE (0.58) NPC1KMT2ARAB9AGAAMAPT
SCHEMBL4642005 0.83 KMT2A (0.56) NPC1KMT2ARAB9AGAAMAPT
SCHEMBL4641719 0.82 KMT2A (0.50) NPC1KMT2ARAB9AGAAMAPT
SCHEMBL27913390 0.81 LCK (0.53) KMT2AMAPTHPGDSMN1; SMN2MEN1
SCHEMBL11201050 0.81 NPC1 (0.57) NPC1KMT2ARAB9AGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed