SCHEMBL4647639

SCHEMBL4647639

CC(C)(C)C(Cl)C(=O)O[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MAPT P10636 3/20 0.35
HSP90AA1 P07900 1/20 0.35
GPR55 Q9Y2T6 1/20 0.35
ALDH1A1 P00352 4/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
TSHR P16473 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
NPC1 O15118 1/20 0.31
ADRB2 P07550 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4644892 0.81 ATM (0.39) ATML3MBTL1MAPTALDH1A1KMT2A
SCHEMBL7055132 0.80 ALDH1A1 (0.38) ATML3MBTL1MAPTALDH1A1KMT2A
SCHEMBL6054093 0.77 ELANE (0.43) ATML3MBTL1MAPTALDH1A1KMT2A
SCHEMBL4644582 0.73 ELANE (0.35) ATML3MBTL1MAPTALDH1A1LMNA
SCHEMBL2711943 0.72 ALDH1A1 (0.43) MAPTHSP90AA1ALDH1A1LMNAGAA
SCHEMBL8808719 0.70 ATM (0.35) ATML3MBTL1MAPTHSP90AA1GPR55
SCHEMBL21065529 0.69 TSHR (0.42) L3MBTL1MAPTALDH1A1LMNACES2
SCHEMBL7848050 0.69 MAPK1 (0.31) TSHR
SCHEMBL4275919 0.69 CYP1A2 (0.38) ATMMAPTALDH1A1KMT2ALMNA
SCHEMBL6555706 0.69 ALDH1A1 (0.39) MAPTALDH1A1KMT2ALMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed