Sugi Predict

Sugi Predict / Compounds / Phenylalanine

Phenylalanine

Phenylalanine

SCHEMBL464777

CSCC[C@H](N)C(=O)O.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 2/20 0.69
▸ ALPI P09923 1/20 0.69
▸ PKM P14618 1/20 0.69
▸ PTGS1 P23219 1/20 0.69
▸ XIAP P98170 1/20 0.69
▸ SLC1A3 P43003 1/20 0.51
▸ SLC1A2 P43004 1/20 0.51
▸ SLC1A1 P43005 1/20 0.51
▸ KMT2A Q03164 1/20 0.48
▸ NOS3 P29474 2/20 0.48
▸ NOS1 P29475 2/20 0.48
▸ NOS2 P35228 2/20 0.48
▸ SLC15A1 P46059 1/20 0.47
▸ FNTA P49354 3/20 0.47
▸ FNTB P49356 3/20 0.47
▸ PGGT1B P53609 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenylalanine SCHEMBL28231547 1.00 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL29503517 1.00 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28076342 1.00 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL464776 1.00 SLC7A5 (0.69) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL23924471 0.94 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL6753059 0.94 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL6276488 0.94 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL7089920 0.94 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL10775098 0.93 SLC7A5 (0.59) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL22500849 0.93 SLC7A5 (0.59) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117717600-A Proliferation agent for promoting growth of lactobacillus plantarum in tumor 光明乳业股份有限公司 2024-03-19 — — CN claimed
CN-117024291-A Alkoxylated ester amines and salts thereof 巴斯夫欧洲公司 2023-11-10 — — CN claimed
US-11484607-B2 PSMA-targeted NIR dyes and their uses On Target Laboratories, LLC (US) 2022-11-01 — — US claimed
US-20210046194-A1 PSMA-TARGETED NIR DYES AND THEIR USES On Target Laboratories, Inc. 2021-02-18 — — US claimed
EP-3347019-A1 PSMA-TARGETED NIR DYES AND THEIR USES On Target Laboratories, LLC (US) 2018-07-18 — — EP claimed
EP-3277098-A1 NOVEL AND USEFUL EDIBLE SALT AND METHODS OF USE AND PRODUCTION THEREOF E.k.salt Ltd. (IL) 2018-02-07 — — EP claimed
US-20170319717-A1 PSMA-TARGETED NIR DYES AND THEIR USES On Target Laboratories, Inc. 2017-11-09 — — US claimed
US-9801956-B2 PSMA-targeted NIR dyes and their uses On Target Laboratories, LLC (US) 2017-10-31 — — US claimed
US-20170281801-A1 PSMA-TARGETED NIR DYES AND THEIR USES On Target Laboratories, Inc. 2017-10-05 — — US claimed
WO-2017044584-A1 PSMA-TARGETED NIR DYES AND THEIR USES On Target Laboratories, LLC (US) 2017-03-16 — — WO claimed
EP-1828243-A2 GROWTH HORMONE SECRETAGOGUE RECEPTOR 1A LIGANDS Gastrotech Pharma A/S (DK) 2007-09-05 — — EP claimed
WO-2006058539-A2 GROWTH HORMONE SECRETAGOGUE RECEPTOR 1A LIGANDS GASTROTECH PHARMA A/S (DK) 2006-06-08 — — WO claimed
WO-2006031844-A2 TREATING THE CAUSE OF BACK PAIN WITH TRACTION WITHIN HYPERBARIC CHAMBER YEUNG JEFFREY E (US) 2006-03-23 — — WO claimed
EP-1383793-A2 INSULIN AND IGF-1 RECEPTOR AGONISTS AND ANTAGONISTS DGI BioTechnologies, L.L.C. (US) 2004-01-28 — — EP claimed
WO-2001072771-A2 INSULIN AND IGF-1 RECEPTOR AGONISTS AND ANTAGONISTS DGI BIOTECHNOLOGIES, L.L.C. (US) 2001-10-04 — — WO claimed
EP-0923287-A4 NONCLASSICAL PYRROLO 2,3-D]PYRIMIDINE ANTIFOLATES LILLY CO ELI (US) 2001-08-01 — — EP claimed
EP-0923287-A1 NONCLASSICAL PYRROLO 2,3-D]PYRIMIDINE ANTIFOLATES ELI LILLY AND COMPANY (US) 1999-06-23 — — EP claimed
WO-1998008382-A1 NONCLASSICAL PYRROLO[2,3-D]PYRIMIDINE ANTIFOLATES ELI LILLY AND COMPANY (US) 1998-03-05 — — WO claimed
US-5304658-A Quinone derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-04-19 — — US claimed
EP-0331404-A2 Method for producing tropane alkaloid SEITAIKINOU RIYOU KAGAKUHIN SHINSEIZOUGIJUTSU KENKYU KUMIAI (JP) 1989-09-06 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210046194-A1 PSMA-TARGETED NIR DYES AND THEIR USES KLK3, FOLH1, CD47 SLC7A5 854/4885ALPI 447/4885PKM 892/4885
US-20170281801-A1 PSMA-TARGETED NIR DYES AND THEIR USES KLK3, FOLH1, CD47 SLC7A5 854/4885ALPI 447/4885PKM 892/4885
US-11484607-B2 PSMA-targeted NIR dyes and their uses KLK3, FOLH1, CD47 SLC7A5 854/4885ALPI 447/4885PKM 892/4885
US-20170319717-A1 PSMA-TARGETED NIR DYES AND THEIR USES KLK3, FOLH1, CD47 SLC7A5 854/4885ALPI 447/4885PKM 892/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.