Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 4/20 | 0.33 |
| ▸ | THRA | P10827 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4644190 | 0.89 | HSD17B10 (0.38) | HSD17B10THRBTHRAESR1NR3C1 | |
| SCHEMBL4642291 | 0.89 | HSD17B10 (0.35) | HSD17B10THRBTHRAESR1NR3C1 | |
| SCHEMBL4644810 | 0.86 | ERN1 (0.44) | HSD17B10MEN1KMT2A | |
| SCHEMBL4642204 | 0.85 | HSD17B10 (0.42) | HSD17B10THRBTHRAAKR1C4AKR1C3 | |
| SCHEMBL4646760 | 0.83 | HSD17B10 (0.41) | HSD17B10THRBTHRAESR1NR3C1 | |
| SCHEMBL9169212 | 0.83 | HSD17B10 (0.41) | HSD17B10THRBTHRAAKR1C4AKR1C3 | |
| SCHEMBL4642410 | 0.82 | POLB (0.36) | TSHRMEN1KMT2A | |
| SCHEMBL4645094 | 0.81 | HSD17B10 (0.40) | HSD17B10THRBTHRAESR1NR3C1 | |
| SCHEMBL4642139 | 0.80 | VCAM1 (0.43) | HSD17B10THRBTHRAAKR1C4AKR1C3 | |
| SCHEMBL4644082 | 0.79 | KDM4E (0.36) | HSD17B10THRBTHRAESR1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487928-B1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2008-08-13 | — | — | EP | disclosed |
| EP-1487928-A1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | Jotun AS (NO) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003080747-A1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2003-10-02 | — | — | WO | disclosed |