Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14633739 | 0.93 | ALDH1A1 (0.60) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL14816323 | 0.93 | ALDH1A1 (0.60) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL21373878 | 0.89 | ALDH1A1 (0.66) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL4647901 | 0.86 | TSHR (0.39) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL10802193 | 0.85 | ALDH1A1 (0.51) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL11684738 | 0.85 | ALDH1A1 (0.73) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL2404660 | 0.85 | ALDH1A1 (0.73) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL8432292 | 0.84 | ALDH1A1 (0.71) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL19178450 | 0.84 | TSHR (0.44) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL123922 | 0.83 | TSHR (0.55) | ALDH1A1TSHRMAPK1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1591098-B1 | Cationically curable composition for dental use | TOKUYAMA CORP (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-7365106-B2 | Cationically curable composition for dental use | TOKUYAMA CORPORATION (JP) | 2008-04-29 | — | — | US | disclosed |
| US-20050250868-A1 | Cationically curable composition for dental use | TOKUYAMA CORPORATION (JP) | 2005-11-10 | — | — | US | disclosed |
| EP-1591098-A1 | Cationically curable composition for dental use | TOKUYAMA CORPORATION (JP) | 2005-11-02 | — | — | EP | disclosed |