SCHEMBL4648

SCHEMBL4648

c1csc(-c2nccs2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.56
KDM4E B2RXH2 7/20 0.50
L3MBTL1 Q9Y468 4/20 0.50
RAB9A P51151 4/20 0.50
MEN1 O00255 2/20 0.50
MAPT P10636 2/20 0.50
HPGD P15428 2/20 0.50
KMT2A Q03164 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
CASP3 P42574 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
ALDH1A1 P00352 3/20 0.48
CYP2A6 P11509 2/20 0.48
EPHX2 P34913 1/20 0.48
HSD17B10 Q99714 1/20 0.48
CYP19A1 P11511 1/20 0.47
CYP2E1 P05181 1/20 0.47
CYP3A4 P08684 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL29229946 0.98 PDPK1 (0.54) PDPK1KDM4EL3MBTL1RAB9AMEN1
SCHEMBL585677 0.86 DPP4 (0.49) PDPK1KDM4EL3MBTL1RAB9AMEN1
SCHEMBL585381 0.86 DPP4 (0.49) PDPK1KDM4EL3MBTL1RAB9AMEN1
SCHEMBL6673347 0.84 PDPK1 (0.50) PDPK1KDM4EL3MBTL1RAB9AMEN1
SCHEMBL11148546 0.80 KDM4E (0.69) KDM4EL3MBTL1RAB9AMEN1MAPT
SCHEMBL30476788 0.77 KDM4E (0.52) KDM4EL3MBTL1RAB9AMEN1MAPT
SCHEMBL2355712 0.77 KMT2A (0.55) PDPK1KDM4EL3MBTL1RAB9AMEN1
SCHEMBL11148541 0.76 PDPK1 (0.42) PDPK1KDM4EL3MBTL1RAB9AMEN1
SCHEMBL12211205 0.76 PDPK1 (0.50) PDPK1KDM4EL3MBTL1RAB9AMEN1
SCHEMBL10013464 0.76 PDPK1 (0.46) PDPK1MAPTCYP2A6CYP19A1CYP2E1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 11977 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12410131-B2 Method for preparation of trans-n-benzyloxycarbonyl-(3-hydroxy-2-piperidinyl)-2-propanone as intermediate of halofuginone CHENGDA PHARMACEUTICALS CO., LTD. (CN) 2025-09-09 US claimed
US-20250147211-A1 LAMINATE, MANUFACTURING METHOD OF LAMINATE, AND VIRTUAL REALITY DISPLAY APPARATUS FUJIFILM CORPORATION (JP) 2025-05-08 US claimed
CN-119744360-A Laminate, method for manufacturing laminate, and virtual reality display device 富士胶片株式会社 2025-04-01 CN claimed
CN-119521943-A Light emitting element and display device including the same 三星显示有限公司 2025-02-25 CN claimed
CN-119462772-A Organometallic complexes, process for their preparation and their use 山东大学 2025-02-18 CN claimed
US-12049583-B2 Compound, composition for anisotropic dye films including the compound, anisotropic dye film, and optical element MITSUBISHI CHEMICAL CORPORATION (JP) 2024-07-30 US claimed
CN-118317956-A Bis (hetero) aryl thioether oxadiazines as fungicidal compounds 拜耳公司 2024-07-09 CN claimed
CN-117886811-A Method for in-situ efficient synthesis of thienyl thiazole compound 南京欧纳壹有机光电有限公司 2024-04-16 CN claimed
EP-4337220-A1 SELECTIVE, PARTIAL, AND ARRESTIN-BIASED 5-HT2A AGONISTS WITH UTILITY IN VARIOUS DISORDERS Saint Joseph's University (US) 2024-03-20 EP claimed
WO-2024048194-A1 LAYERED BODY, METHOD FOR MANUFACTURING LAYERED BODY, AND VIRTUAL REALITY DISPLAY DEVICE 富士フイルム株式会社 2024-03-07 WO claimed
EP-0183191-B1 THIENYLTHIAZOLE COMPOUNDS Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1989-05-10 EP claimed
US-4752558-A Light-sensitive silver halide color photographic material KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1988-06-21 US claimed
US-4720493-A Thienylthiazole compounds YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1988-01-19 US claimed
WO-1987006429-A1 PHOTOACTIVE AZOLE PESTICIDES FMC CORPORATION (US) 1987-11-05 WO claimed
EP-0121825-B1 MONOAZO DYESTUFFS FOR CELLULOSE-CONTAINING FIBERS MITSUBISHI KASEI CORPORATION (JP) 1986-09-10 EP claimed
EP-0183191-A1 Thienylthiazole compounds Yoshitomi Pharmaceutical Industries, Ltd. (JP) 1986-06-04 EP claimed
EP-0103158-B1 THIENO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM Dr. Karl Thomae GmbH (DE) 1986-02-26 EP claimed
US-4551460-A ANTICOAGULANTS, CARDIOVASCULAR DISORDERS HOFFMANN-LA ROCHE INC. (US) 1985-11-05 US claimed
EP-0150939-A1 Dihydropyridine anti-ischaemic and antihypertensive agents Pfizer Limited (GB) 1985-08-07 EP claimed
EP-0121825-A1 Monoazo dyestuffs for cellulose-containing fibers MITSUBISHI KASEI CORPORATION (JP) 1984-10-17 EP claimed