SCHEMBL6673347

SCHEMBL6673347

c1csc(-c2ccccc2-c2nccs2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 1/20 0.50
RAB9A P51151 6/20 0.41
LTA4H P09960 1/20 0.41
CYP2A6 P11509 2/20 0.41
ADRA1A P35348 3/20 0.40
ADRA1D P25100 2/20 0.40
ADRA1B P35368 2/20 0.40
ADORA2A P29274 1/20 0.40
ADORA1 P30542 1/20 0.40
CYP19A1 P11511 1/20 0.40
ADRA2A P08913 1/20 0.40
NPC1 O15118 4/20 0.39
METAP1 P53582 1/20 0.39
ATM Q13315 1/20 0.39
LTK P29376 1/20 0.39
CDK5 Q00535 1/20 0.39
MST1R Q04912 1/20 0.39
DYRK1A Q13627 1/20 0.39
CLK4 Q9HAZ1 1/20 0.39
CYP2E1 P05181 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5692672 0.86 PDPK1 (0.64) PDPK1RAB9ACYP2A6ADRA1AADRA1D
SCHEMBL1951149 0.84 PDPK1 (0.61) PDPK1RAB9ACYP2A6ADRA1AADRA1D
SCHEMBL4648 0.84 PDPK1 (0.56) PDPK1RAB9ACYP2A6CYP19A1NPC1
Bromide SCHEMBL29229946 0.82 PDPK1 (0.54) PDPK1RAB9ACYP2A6CYP19A1NPC1
SCHEMBL995326 0.79 LTA4H (0.55) RAB9ALTA4HCYP2A6NPC1ATM
Hydrogen Sulfide SCHEMBL752785 0.77 LTA4H (0.53) RAB9ALTA4HCYP2A6NPC1ATM
SCHEMBL2175845 0.77 PDPK1 (0.70) PDPK1RAB9ACYP2A6ADRA1AADRA1D
SCHEMBL585381 0.76 DPP4 (0.49) PDPK1RAB9ALTA4HCYP2A6CYP19A1
SCHEMBL585677 0.76 DPP4 (0.49) PDPK1RAB9ALTA4HCYP2A6CYP19A1
SCHEMBL20899926 0.75 CA2 (0.45) KDM4EALDH1A1L3MBTL1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004026989-A1 LUMINESCENT MIXTURES BASF AKTIENGESELLSCHAFT (DE) 2004-04-01 WO disclosed