SCHEMBL4648142

SCHEMBL4648142

CC(C)(COC(=O)c1ccc(C(=O)O)cc1)COC(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 1/20 0.56
MAPK1 P28482 2/20 0.53
HIF1A Q16665 1/20 0.53
MAPT P10636 1/20 0.53
ALDH1A1 P00352 5/20 0.48
TDP1 Q9NUW8 2/20 0.47
HTR1A P08908 1/20 0.47
CYP2D6 P10635 1/20 0.47
SCN1A P35498 1/20 0.47
SLC6A3 Q01959 1/20 0.47
SCN5A Q14524 1/20 0.47
SCN2A Q99250 1/20 0.47
SCN3A Q9NY46 1/20 0.47
TSHR P16473 3/20 0.46
TP53 P04637 1/20 0.46
KMT2A Q03164 1/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
ESR1 P03372 2/20 0.44
SRD5A2 P31213 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3453488 0.91 MAPT (0.49) SERPINE1MAPK1HIF1AMAPTALDH1A1
SCHEMBL10348750 0.89 MAPK1 (0.51) SERPINE1MAPK1HIF1AMAPTALDH1A1
Terephthalic Acid SCHEMBL2442144 0.89 MAPK1 (0.53) SERPINE1MAPK1HIF1AMAPTALDH1A1
SCHEMBL3453675 0.89 MAPK1 (0.53) SERPINE1MAPK1HIF1AMAPTALDH1A1
Ethylene Glycol SCHEMBL11412767 0.88 MAPT (0.46) SERPINE1MAPK1HIF1AMAPTALDH1A1
SCHEMBL27800544 0.87 MAPK1 (0.52) SERPINE1MAPK1HIF1AMAPTALDH1A1
SCHEMBL11613334 0.87 ALDH1A1 (0.49) SERPINE1MAPK1HIF1AMAPTALDH1A1
SCHEMBL204567 0.86 MAPK1 (0.71) SERPINE1MAPK1HIF1AMAPTALDH1A1
SCHEMBL29662716 0.85 MAPT (0.48) SERPINE1MAPK1HIF1AMAPTALDH1A1
Benzoic Acid SCHEMBL11514556 0.85 MAPK1 (0.56) SERPINE1MAPK1HIF1AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1280010-B1 Crosslinked binder polymers for electrostatographic toners and toners formed therefrom EASTMAN KODAK CO (US) 2008-08-27 EP claimed
US-6861192-B2 Crosslinked binder polymers for electrostatographic toners and toners formed therefrom EASTMAN KODAK COMPANY (US) 2005-03-01 US claimed
US-20030069368-A1 Crosslinked binder polymers for electrostatographic toners and toners formed therefrom BANK OF AMERICA, N.A., AS AGENT 2003-04-10 US claimed
EP-1280010-A2 Crosslinked binder polymers for electrostatographic toners and toners formed therefrom Heidelberger Druckmaschinen Aktiengesellschaft (DE) 2003-01-29 EP claimed
US-4157419-A THREE DIFFERENT KINDS OF FILAMENTS INCLUDING ECCENTRIC BICOMPONENT FILAMENT OF FIRST TWO E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-06-05 US claimed
US-4115989-A Product and process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-09-26 US claimed
CN-113956455-A Poly-modified 2, 2-dimethyl-1, 3-propylene glycol ester and preparation method and application thereof 中国石油化工股份有限公司 2022-01-21 CN disclosed
EP-1280010-B1 Crosslinked binder polymers for electrostatographic toners and toners formed therefrom EASTMAN KODAK CO (US) 2008-08-27 EP disclosed
US-6861192-B2 Crosslinked binder polymers for electrostatographic toners and toners formed therefrom EASTMAN KODAK COMPANY (US) 2005-03-01 US disclosed
US-20030069368-A1 Crosslinked binder polymers for electrostatographic toners and toners formed therefrom BANK OF AMERICA, N.A., AS AGENT 2003-04-10 US disclosed
EP-1280010-A2 Crosslinked binder polymers for electrostatographic toners and toners formed therefrom Heidelberger Druckmaschinen Aktiengesellschaft (DE) 2003-01-29 EP disclosed
US-4096341-A MONOMERS FOR POLYESTERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-06-20 US disclosed
US-4085091-A Thermally stable, rigid polyesters from thermally stable, rigid dibasic acids and aromatic dihydroxy compounds E. I. DUPONT DE NEMOURS AND COMPANY (US) 1978-04-18 US disclosed