Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propanol SCHEMBL28053966 | 0.90 | ALDH1A1 (0.48) | ALDH1A1CYP1A2HPGDHSD17B10THRB | |
| Propane SCHEMBL27966209 | 0.89 | ALDH1A1 (0.57) | ALDH1A1CYP1A2HPGDHSD17B10THRB | |
| Benzo[E]Pyrene SCHEMBL27983847 | 0.88 | ALDH1A1 (0.73) | ALDH1A1CYP1A2HPGDHSD17B10THRB | |
| Ethylene Glycol SCHEMBL4050504 | 0.86 | ALDH1A1 (0.55) | ALDH1A1CYP1A2HPGDHSD17B10THRB | |
| Methyl Alcohol SCHEMBL27921828 | 0.86 | ALDH1A1 (0.60) | ALDH1A1CYP1A2HPGDHSD17B10THRB | |
| Pyrene SCHEMBL1274682 | 0.83 | ALDH1A1 (0.65) | ALDH1A1CYP1A2HPGDHSD17B10THRB | |
| Ethane SCHEMBL27966439 | 0.83 | ALDH1A1 (0.63) | ALDH1A1CYP1A2HPGDHSD17B10THRB | |
| SCHEMBL634848 | 0.83 | ALDH1A1 (0.71) | ALDH1A1CYP1A2HPGDHSD17B10THRB | |
| SCHEMBL29906043 | 0.83 | ALDH1A1 (0.71) | ALDH1A1CYP1A2HPGDHSD17B10THRB | |
| SCHEMBL26440 | 0.83 | ALDH1A1 (0.71) | ALDH1A1CYP1A2HPGDHSD17B10THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1903609-A2 | Method for manufacturing a thin film transistor array panel | Samsung Electronics Co., Ltd. (KR) | 2008-03-26 | — | — | EP | disclosed |