SCHEMBL4648286

SCHEMBL4648286

COc1ccccc1OC(=O)CCCO

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.52
MAPT P10636 3/20 0.52
MEN1 O00255 3/20 0.52
ALDH1A1 P00352 3/20 0.51
POLB P06746 2/20 0.50
KDM4E B2RXH2 1/20 0.50
RECQL P46063 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
LMNA P02545 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.46
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA4 P22748 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
AGTR1 P30556 1/20 0.44
CYP1A2 P05177 1/20 0.44
TOP2A P11388 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4643517 0.95 KMT2A (0.51) KMT2AMAPTMEN1ALDH1A1POLB
SCHEMBL5701570 0.91 KMT2A (0.56) KMT2AMAPTMEN1ALDH1A1POLB
SCHEMBL28936425 0.91 KMT2A (0.56) KMT2AMAPTMEN1ALDH1A1POLB
SCHEMBL4642495 0.89 KMT2A (0.55) KMT2AMAPTMEN1ALDH1A1POLB
SCHEMBL3361882 0.87 KMT2A (0.59) KMT2AMAPTMEN1ALDH1A1POLB
SCHEMBL4085609 0.86 MEN1 (0.67) KMT2AMAPTMEN1ALDH1A1POLB
SCHEMBL4090350 0.85 MEN1 (0.60) KMT2AMAPTMEN1ALDH1A1POLB
SCHEMBL4646799 0.85 KMT2A (0.51) KMT2AMAPTMEN1ALDH1A1POLB
SCHEMBL28847868 0.85 LMNA (0.58) KMT2AMAPTMEN1ALDH1A1POLB
SCHEMBL4646037 0.85 KMT2A (0.51) KMT2AMAPTMEN1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1487928-B1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2008-08-13 EP disclosed
EP-1487928-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT Jotun AS (NO) 2004-12-22 EP disclosed
WO-2003080747-A1 FILM-FORMING POLYMER AND ANTIFOULING PAINT JOTUN AS (NO) 2003-10-02 WO disclosed