SCHEMBL4648408

SCHEMBL4648408

CCCCCCCCCCCCc1ccc(S(=O)(=O)N[N]S(=O)(=O)c2ccc(C)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.53
AKT1 P31749 10/20 0.50
CA2 P00918 2/20 0.49
LMNA P02545 2/20 0.48
HTT P42858 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 1/20 0.48
KMT2A Q03164 1/20 0.48
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
TSHR P16473 1/20 0.47
CYP2C19 P33261 1/20 0.47
KCNH2 Q12809 1/20 0.47
HIF1A Q16665 1/20 0.47
GAB1 Q13480 2/20 0.47
PDPK1 O15530 1/20 0.47
ABCB11 O95342 1/20 0.47
AKT2 P31751 1/20 0.47
AKT3 Q9Y243 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL195574 0.83 CA2 (0.57) KDM4EAKT1CA2LMNAHTT
SCHEMBL8094483 0.80 FFAR1 (0.68) KDM4EAKT1LMNAMEN1ALDH1A1
SCHEMBL12040865 0.78 CA2 (0.62) KDM4EAKT1CA2LMNAHTT
SCHEMBL6637289 0.77 CA2 (0.53) KDM4EAKT1CA2LMNAHTT
SCHEMBL14550114 0.77 CA2 (0.64) KDM4EAKT1CA2LMNAHTT
SCHEMBL26965400 0.77 CA2 (0.64) KDM4EAKT1CA2LMNAHTT
Sulfuric Acid SCHEMBL5702660 0.77 CA2 (0.59) KDM4EAKT1CA2LMNAHTT
SCHEMBL10926573 0.75 CA2 (0.62) KDM4EAKT1CA2LMNAHTT
SCHEMBL4187550 0.75 CA12 (0.54) KDM4ECA2LMNASMN1; SMN2MEN1
SCHEMBL4021550 0.75 CA12 (0.54) KDM4ECA2LMNASMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1897416-A1 ELECTROLUMINESCENT DEVICES WITH NITROGEN BIDENTATE LIGANDS EASTMAN KODAK COMPANY (US) 2008-03-12 EP disclosed
WO-2007005252-A1 ELECTROLUMINESCENT DEVICES WITH NITROGEN BIDENTATE LIGANDS EASTMAN KODAK COMPANY (US) 2007-01-11 WO disclosed