Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4644970 | 0.84 | PTPN1 (0.53) | PTPN1PTPN2 | |
| SCHEMBL2934032 | 0.82 | PTPN1 (0.70) | PTPN1PTPN2 | |
| SCHEMBL4646595 | 0.81 | PTPN1 (0.53) | PTPN1 | |
| SCHEMBL2933303 | 0.78 | PTPN1 (0.65) | PTPN1PTPN2 | |
| SCHEMBL3210021 | 0.78 | PTPN1 (0.61) | PTPN1PTPN2 | |
| SCHEMBL2937571 | 0.76 | PTPN1 (0.65) | PTPN1PTPN2 | |
| SCHEMBL2937609 | 0.76 | PTPN1 (0.58) | PTPN1PTPN2 | |
| SCHEMBL14035112 | 0.76 | PTPN1 (0.65) | PTPN1PTPN2 | |
| SCHEMBL2936747 | 0.76 | PTPN1 (0.65) | PTPN1PTPN2 | |
| SCHEMBL2935490 | 0.76 | PTPN1 (0.65) | PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960377-A1 | l , l , 3-TRI0X0-l , 2 , 5-THIADIAZ0LIDINES AND THEIR USE AS PTP-ASES INHIBITORS | Novartis AG (CH) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007067614-A1 | l, l, 3-TRI0X0-l, 2, 5-THIADIAZ0LIDINES AND THEIR USE AS PTP-ASES INHIBITORS | NOVARTIS AG (CH) | 2007-06-14 | — | — | WO | disclosed |