Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.66 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2704556 | 0.90 | SLC22A6 (0.74) | SLC22A6PBRM1GPR84NR4A2CREBBP | |
| SCHEMBL6261233 | 0.86 | SLC22A6 (0.70) | SLC22A6PBRM1GPR84NR4A2CREBBP | |
| SCHEMBL9047908 | 0.85 | SLC22A6 (0.68) | SLC22A6PBRM1GPR84NR4A2CREBBP | |
| SCHEMBL125250 | 0.83 | SLC22A6 (0.76) | SLC22A6PBRM1GPR84NR4A2CREBBP | |
| SCHEMBL27729377 | 0.82 | SLC22A6 (0.74) | SLC22A6PBRM1GPR84NR4A2CREBBP | |
| SCHEMBL11042304 | 0.82 | SLC22A6 (0.73) | SLC22A6PBRM1GPR84NR4A2CREBBP | |
| SCHEMBL23295617 | 0.81 | SLC22A6 (0.72) | SLC22A6PBRM1GPR84NR4A2CREBBP | |
| SCHEMBL1831734 | 0.81 | SLC22A6 (0.72) | SLC22A6PBRM1GPR84NR4A2CREBBP | |
| SCHEMBL2001612 | 0.80 | SLC22A6 (0.65) | SLC22A6PBRM1GPR84NR4A2CREBBP | |
| SCHEMBL28768822 | 0.79 | SLC22A6 (0.70) | SLC22A6PBRM1GPR84NR4A2CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111349088-B | Indole-based heterocyclic compounds, preparation method thereof and application thereof in controlling plant diseases | 天津师范大学 | 2022-09-20 | — | — | CN | claimed |
| CN-111349088-A | Indole-based heterocyclic compounds, preparation method thereof and application thereof in controlling plant diseases | 天津师范大学 | 2020-06-30 | — | — | CN | claimed |
| CN-111349089-A | Indole heterocyclic compound, preparation method thereof and application thereof in preventing and treating plant diseases | 天津师范大学 | 2020-06-30 | — | — | CN | claimed |
| CN-111349089-B | Indole heterocyclic compounds, preparation method thereof and application thereof in preventing and treating plant diseases | 天津师范大学 | 2022-11-29 | — | — | CN | disclosed |
| CN-111349089-B | Indole heterocyclic compounds, preparation method thereof and application thereof in preventing and treating plant diseases | 天津师范大学 | 2022-11-29 | — | — | CN | disclosed |
| CN-111349088-B | Indole-based heterocyclic compounds, preparation method thereof and application thereof in controlling plant diseases | 天津师范大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-111349088-B | Indole-based heterocyclic compounds, preparation method thereof and application thereof in controlling plant diseases | 天津师范大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-111349088-A | Indole-based heterocyclic compounds, preparation method thereof and application thereof in controlling plant diseases | 天津师范大学 | 2020-06-30 | — | — | CN | disclosed |
| CN-111349088-A | Indole-based heterocyclic compounds, preparation method thereof and application thereof in controlling plant diseases | 天津师范大学 | 2020-06-30 | — | — | CN | disclosed |
| CN-111349089-A | Indole heterocyclic compound, preparation method thereof and application thereof in preventing and treating plant diseases | 天津师范大学 | 2020-06-30 | — | — | CN | disclosed |
| CN-111349089-A | Indole heterocyclic compound, preparation method thereof and application thereof in preventing and treating plant diseases | 天津师范大学 | 2020-06-30 | — | — | CN | disclosed |
| CN-101312722-A | Modulators of atp-binding cassette transporters | VERTEX PHARMA (US) | 2008-11-26 | — | — | CN | disclosed |
| EP-1675830-A4 | HETEROCYCLIC AMIDES AND SULFONAMIDES | SCIOS INC (US) | 2008-08-20 | — | — | EP | disclosed |
| US-20060199821-A1 | Heterocyclic amides and sulfonamides | SCIOS, INC. (US) | 2006-09-07 | — | — | US | disclosed |
| EP-1675830-A2 | HETEROCYCLIC AMIDES AND SULFONAMIDES | SCIOS INC. (US) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005033072-A2 | HETEROCYCLIC AMIDES AND SULFONAMIDES | SCIOS INC. (US) | 2005-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060199821-A1 | Heterocyclic amides and sulfonamides | MAP4K2, MAP3K8, MAP3K2 | SLC22A6 3388/4885PBRM1 2963/4885GPR84 1769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.