SCHEMBL125250

SCHEMBL125250

CC(=O)C(=O)Oc1c[nH]c2ccccc12

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 2/20 0.76
PBRM1 Q86U86 1/20 0.57
NR4A2 P43354 2/20 0.49
CREBBP Q92793 1/20 0.49
GPR84 Q9NQS5 1/20 0.47
LMNA P02545 2/20 0.47
ALDH1A1 P00352 2/20 0.45
ATM Q13315 2/20 0.45
GSK3B P49841 1/20 0.44
KDM4E B2RXH2 1/20 0.44
APAF1 O14727 1/20 0.44
POLB P06746 1/20 0.44
MAPT P10636 1/20 0.44
RECQL P46063 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CTNNB1 P35222 1/20 0.43
WNT3A P56704 1/20 0.43
PKM P14618 2/20 0.43
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2704556 0.90 SLC22A6 (0.74) SLC22A6PBRM1NR4A2CREBBPGPR84
SCHEMBL11042304 0.89 SLC22A6 (0.73) SLC22A6PBRM1NR4A2CREBBPGPR84
Indole Acetate SCHEMBL15553 0.86 SLC22A6 (1.00) SLC22A6PBRM1NR4A2CREBBPGPR84
Indole Acetate SCHEMBL14576593 0.85 SLC22A6 (0.97) SLC22A6PBRM1NR4A2CREBBPGPR84
SCHEMBL9047908 0.85 SLC22A6 (0.68) SLC22A6PBRM1NR4A2CREBBPGPR84
Indole Acetate SCHEMBL14576776 0.85 SLC22A6 (0.97) SLC22A6PBRM1NR4A2CREBBPGPR84
Indole Acetate SCHEMBL28825383 0.85 SLC22A6 (0.97) SLC22A6PBRM1NR4A2CREBBPGPR84
SCHEMBL27637192 0.84 SLC22A6 (0.68) SLC22A6PBRM1NR4A2CREBBPGPR84
SCHEMBL4648476 0.83 SLC22A6 (0.66) SLC22A6PBRM1NR4A2CREBBPGPR84
SCHEMBL2001612 0.83 SLC22A6 (0.65) SLC22A6PBRM1NR4A2CREBBPGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1808 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
EP-4739326-A2 PRODUCTION & SECRETION OF AUXIN-LIKE MOLECULES IN BACTERIA SNIPR Biome ApS (DK) 2026-05-13 EP claimed
US-20260123658-A1 Methods of Increasing the Beneficial Properties of Fermented Foods The Brd. of Trustees of the Univ. of Illinois (US) 2026-05-07 US claimed
EP-3690042-B1 PARTHENOCARPY REGULATION GENE AND USE THEREOF NATIONAL RES AND DEVELOPMENT AGENCY NATIONAL AGRICULTURE AND FOOD RES ORGANIZATION (JP) 2026-05-06 EP claimed
EP-3796922-B1 PHARMACEUTICAL COMPOSITIONS COMPRISING A SELENO AMINO ACID COMPOUND FOR USE IN COMBINATION WITH ANOTHER AGENT FOR THE TREATMENT OF LIVER OR PANCREAS CANCER SELEQ OY (FI) 2026-03-18 EP claimed
EP-4677086-A1 PROTECTION OF PLANTS AGAINST PATHOGENS BY INDUCTION OF SYSTEMIC OR LOCALIZED PROTECTIVE RESPONSES IN PLANTS Greenlight Biosciences, Inc. (US) 2026-01-14 EP claimed
EP-4633627-A1 COSMETIC USE OF A COMPOSITION FOR CARING FOR KERATIN MATERIALS COMPRISING AT LEAST INDOLE-3-PYRUVIC ACID L'OREAL (FR) 2025-10-22 EP claimed
US-12435294-B2 Prevention of the oxidation of perfumery raw materials and food raw materials FIRMENICH SA (CH) 2025-10-07 US claimed
US-20250268959-A1 COMPOSITIONS CONTAINING INDOLE-DERIVED METABOLITES AND METHODS OF USE THEREOF Imvela Corp. (US) 2025-08-28 US claimed
US-12318414-B2 Method and system to modify an individual's gut-brain axis to provide neurocognitive protection SEED HEALTH, INC. (US) 2025-06-03 US claimed
EP-0673782-A2 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORPORATION (US) 1995-09-27 EP claimed
US-5210215-A Reacting indoles, dimethylamine and formaldehyde to gramines, condensing with malonic compounds to tryptophans, converting to 3-indolepyruvic acids; also preparation from indoles by reaction with alkyl ester oximes of 3-bromopyruvic acid POLIFARMA S.P.A. (IT) 1993-05-11 US claimed
EP-0188712-B1 PROCESS FOR OBTAINING PHENYL ALANINE-CONTAINING MICROORGANISMS AND THEIR USE IN THE PREPARATION OF L-ALPHA-AMINO ACIDS Degussa Aktiengesellschaft (DE) 1990-01-31 EP claimed
US-4859591-A Transamination process for producing amino acids W. R. GRACE & CO.-CONN. (US) 1989-08-22 US claimed
EP-0120208-B1 MICROBIOLOGICALLY PRODUCED L-PHENYLALANIN-DEHYDROGENASE, PROCESS FOR OBTAINING IT AND ITS USE Degussa Aktiengesellschaft (DE) 1989-03-22 EP claimed
CN-85107547-A Microchemiluminescent detection system 1987-04-15 CN claimed
US-4590161-A AEROBIC CULTIVATION OF BREUIBACTERIUM DEGUSSA AKTIENGESELLSCHAFT (DE) 1986-05-20 US claimed
EP-0175577-A2 Microchemiluminescent assay system Kiel, Jonathan L (US) 1986-03-26 EP claimed
EP-0162920-A1 METHOD OF CATALYZING CHEMICAL REACTIONS IGEN, INC. (a California corporation) (US) 1985-12-04 EP claimed
WO-1985002414-A1 METHOD OF CATALYZING CHEMICAL REACTIONS IGEN, INC. (US) 1985-06-06 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12435294-B2 Prevention of the oxidation of perfumery raw materials and food raw materials CUTA, MPO, GPX4 SLC22A6 3941/4885PBRM1 3710/4885NR4A2 3003/4885
US-20260123658-A1 Methods of Increasing the Beneficial Properties of Fermented Foods AADAT, IDO1, ALDOA SLC22A6 702/4885PBRM1 2684/4885NR4A2 2297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.