Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | RBP4 | P02753 | 2/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2785015 | 0.77 | MEN1 (0.47) | L3MBTL1ALDH1A1PPARGHTTNPSR1 | |
| SCHEMBL4648484 | 0.74 | PPARG (0.63) | MAPTLMNAPPARG | |
| SCHEMBL4648480 | 0.74 | PPARG (0.63) | MAPTLMNAPPARG | |
| SCHEMBL4646268 | 0.74 | PPARG (0.56) | MAPTLMNAPPARG | |
| SCHEMBL4646262 | 0.74 | PPARG (0.56) | MAPTLMNAPPARG | |
| SCHEMBL4068968 | 0.70 | PPARG (0.56) | PPARG | |
| SCHEMBL4685110 | 0.67 | PPARG (0.64) | MAPTLMNAPPARG | |
| SCHEMBL4685115 | 0.67 | PPARG (0.64) | MAPTLMNAPPARG | |
| SCHEMBL4648132 | 0.66 | PPARG (0.57) | MAPTLMNAPPARG | |
| SCHEMBL4648141 | 0.66 | PPARG (0.57) | MAPTLMNAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778624-B1 | TYROSINE DERIVATIVES AS PPAR-GAMMA-MODULATORS | SALVAT LAB SA (ES) | 2008-08-20 | — | — | EP | disclosed |