Succinic Acid Diethyl Ester

Succinic Acid Diethyl Ester

SCHEMBL4649219

CCOC(=O)CCC(=O)OCC.ClC(Cl)C(Cl)Cl

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.52
MGAM O43451 1/20 0.52
SI P14410 1/20 0.52
MGAM2 Q2M2H8 1/20 0.52
CYP1A2 P05177 1/20 0.52
ALDH1A1 P00352 4/20 0.48
TRPA1 O75762 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.46
POLB P06746 2/20 0.44
LMNA P02545 2/20 0.44
TSHR P16473 1/20 0.44
KMT2A Q03164 2/20 0.43
CYP4F2 P78329 2/20 0.42
CYP4A11 Q02928 2/20 0.42
HSD17B10 Q99714 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NR1I2 O75469 1/20 0.41
PGR P06401 1/20 0.41
ADORA3 P0DMS8 1/20 0.41
PTGS2 P35354 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid Diethyl Ester SCHEMBL27768067 0.87 GAA (0.67) GAAMGAMSIMGAM2CYP1A2
Succinic Acid Diethyl Ester SCHEMBL22780 0.87 GAA (0.67) GAAMGAMSIMGAM2CYP1A2
Succinic Acid Diethyl Ester SCHEMBL11510951 0.86 CYP1A2 (0.48) GAAMGAMSIMGAM2CYP1A2
Chloroform SCHEMBL6641206 0.84 CYP1A2 (0.47) GAAMGAMSIMGAM2CYP1A2
Chloroform SCHEMBL2142434 0.84 CYP1A2 (0.47) GAAMGAMSIMGAM2CYP1A2
Succinic Acid Diethyl Ester SCHEMBL21815758 0.84 GAA (0.63) GAAMGAMSIMGAM2CYP1A2
Succinic Acid Diethyl Ester SCHEMBL4324913 0.84 GAA (0.63) GAAMGAMSIMGAM2CYP1A2
Succinic Acid Diethyl Ester SCHEMBL28853161 0.84 GAA (0.63) GAAMGAMSIMGAM2CYP1A2
Succinic Acid Diethyl Ester SCHEMBL29494609 0.84 GAA (0.63) GAAMGAMSIMGAM2CYP1A2
Succinic Acid Diethyl Ester SCHEMBL27525301 0.84 GAA (0.63) GAAMGAMSIMGAM2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0515096-B2 Method of producing a polymeric composite film DUPONT TEIJIN FILMS US LTD (US) 2008-09-03 EP disclosed
EP-0515096-B1 Polymeric film DU PONT (US) 1999-10-06 EP disclosed
US-5656222-A Method of coating polymeric substrates with particulate materials IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1997-08-12 US disclosed
CN-1069277-A Polymer film ICI PLC (GB) 1993-02-24 CN disclosed
EP-0515096-A2 Polymeric film IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-11-25 EP disclosed