Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 10/20 | 0.72 |
| ▸ | NOS3 | P29474 | 2/20 | 0.70 |
| ▸ | NOS2 | P35228 | 2/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | GART | P22102 | 1/20 | 0.46 |
| ▸ | PAH | P00439 | 1/20 | 0.45 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.43 |
| ▸ | FPGS | Q05932 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9248337 | 1.00 | NOS1 (0.72) | NOS1NOS3NOS2USP2CASP7 | |
| SCHEMBL4649231 | 1.00 | NOS1 (0.72) | NOS1NOS3NOS2USP2CASP7 | |
| SCHEMBL2044797 | 0.84 | NOS1 (0.78) | NOS1NOS3NOS2USP2CASP7 | |
| SCHEMBL31561469 | 0.84 | NOS1 (0.69) | NOS1NOS3NOS2USP2CASP7 | |
| SCHEMBL10854897 | 0.83 | NOS1 (0.83) | NOS1NOS3NOS2USP2CASP7 | |
| SCHEMBL10852056 | 0.83 | NOS1 (0.75) | NOS1NOS3NOS2USP2CASP7 | |
| SCHEMBL10615701 | 0.82 | NOS1 (0.71) | NOS1NOS3NOS2USP2CASP7 | |
| SCHEMBL10618519 | 0.81 | NOS1 (0.91) | NOS1NOS3NOS2USP2CASP7 | |
| SCHEMBL10849648 | 0.79 | NOS1 (0.66) | NOS1NOS3NOS2USP2CASP7 | |
| SCHEMBL584982 | 0.78 | NOS1 (0.64) | NOS1NOS3NOS2USP2CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1964566-A1 | PREPARATION WITH IMPROVED BIOABSORBABILITY OF SAPROPTERIN HYDROCHLORIDE | Asubio Pharma Co., Ltd. (JP) | 2008-09-03 | — | — | EP | disclosed |