Biphenyl

Biphenyl

SCHEMBL4649290

O=C1c2ccccc2C(=O)N1C(=O)N1C(=O)c2ccccc2C1=O.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.48
CA9 Q16790 2/20 0.48
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
SCN2A Q99250 1/20 0.44
KMT2A Q03164 3/20 0.43
POLB P06746 1/20 0.43
ALDH1A1 P00352 2/20 0.42
ASAH1 Q13510 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
LMNA P02545 1/20 0.42
FGFR1 P11362 1/20 0.41
FGFR2 P21802 1/20 0.41
FGFR4 P22455 1/20 0.41
FGFR3 P22607 1/20 0.41
CYP1A2 P05177 1/20 0.41
EHMT2 Q96KQ7 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL238006 0.91 CA12 (0.50) CA12CA9CA1CA2SCN2A
SCHEMBL439730 0.79 CA12 (0.54) CA12CA9CA1CA2SCN2A
SCHEMBL30704939 0.79 CA12 (0.54) CA12CA9CA1CA2SCN2A
SCHEMBL21855119 0.79 CA12 (0.52) CA12CA9CA1CA2SCN2A
SCHEMBL23732653 0.77 CA12 (0.52) CA12CA9CA1CA2SCN2A
Ammonia Solution, Strong SCHEMBL11349034 0.77 CA12 (0.52) CA12CA9CA1CA2SCN2A
Ammonia Solution, Strong SCHEMBL11349044 0.77 CA12 (0.52) CA12CA9CA1CA2SCN2A
Hydrochloric Acid SCHEMBL9592305 0.77 CA12 (0.52) CA12CA9CA1CA2SCN2A
SCHEMBL11277521 0.75 CA12 (0.48) CA12CA9CA1CA2SCN2A
SCHEMBL9686147 0.74 P2RX4 (0.55) CA12CA9CA1CA2SCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1963433-A2 ANNULAR OR TUBULAR SHAPED ARTICLES OF NOVEL POLYMER BLENDS General Electric Company (US) 2008-09-03 EP claimed
EP-1960470-A2 FOOD SERVICE ARTICLES OF MANUFACTURE COMPRISING HIGH TEMPERATURE POLYMERS General Electric Company (US) 2008-08-27 EP claimed
WO-2008091253-A1 HIGH HEAT ELECTRICAL CONNECTORS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2008-07-31 WO claimed
WO-2007078788-A2 FOOD SERVICE ARTICLES OF MANUFACTURE COMPRISING HIGH TEMPERATURE POLYMERS GENERAL ELECTRIC COMPANY (US) 2007-07-12 WO claimed
WO-2007075365-A2 ANNULAR OR TUBULAR SHAPED ARTICLES OF NOVEL POLYMER BLENDS GENERAL ELECTRIC COMPANY (US) 2007-07-05 WO claimed
US-20070142569-A1 Food service articles of manufacture comprising high temperature polymers CITIBANK, N.A., AS COLLATERAL AGENT 2007-06-21 US claimed
US-20070066740-A1 Annular or tubular shaped articles of novel polymer blends CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-22 US claimed
US-20070065615-A1 ANNULAR OR TUBULAR SHAPED ARTICLES OF NOVEL POLYMER BLENDS CITIBANK, N.A., AS COLLATERAL AGENT 2007-03-22 US claimed