Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4474488 | 1.00 | LTA4H (0.48) | LTA4HCNR2ALDH1A1DRD4DRD2 | |
| SCHEMBL4477113 | 1.00 | LTA4H (0.48) | LTA4HCNR2ALDH1A1DRD4DRD2 | |
| SCHEMBL4472810 | 0.89 | CNR2 (0.58) | LTA4HCNR2ALDH1A1SIGMAR1TACR1 | |
| SCHEMBL13708823 | 0.89 | LTA4H (0.47) | LTA4HCNR2ALDH1A1DRD4DRD2 | |
| SCHEMBL4473200 | 0.89 | CNR2 (0.58) | LTA4HCNR2ALDH1A1SIGMAR1TACR1 | |
| SCHEMBL4467570 | 0.89 | LTA4H (0.47) | LTA4HCNR2ALDH1A1DRD4DRD2 | |
| SCHEMBL4469949 | 0.89 | CNR2 (0.58) | LTA4HCNR2ALDH1A1SIGMAR1TACR1 | |
| SCHEMBL4474543 | 0.89 | CNR2 (0.54) | LTA4HCNR2ALDH1A1SIGMAR1ATM | |
| SCHEMBL4472251 | 0.89 | CNR2 (0.54) | LTA4HCNR2ALDH1A1SIGMAR1ATM | |
| SCHEMBL4472249 | 0.89 | CNR2 (0.54) | LTA4HCNR2ALDH1A1SIGMAR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966132-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070760-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-21 | — | — | WO | disclosed |