Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4465145 | 0.89 | CNR2 (1.00) | CNR2MOGAT2 | |
| SCHEMBL4465139 | 0.89 | CNR2 (1.00) | CNR2MOGAT2 | |
| SCHEMBL9523708 | 0.81 | CNR2 (0.58) | CNR2MEN1KMT2ADRD3 | |
| SCHEMBL4473154 | 0.80 | CNR2 (0.79) | CNR2MOGAT2 | |
| SCHEMBL4649659 | 0.78 | CNR2 (0.55) | CNR2MEN1KMT2AMOGAT2DRD3 | |
| SCHEMBL4467525 | 0.78 | CNR2 (0.72) | CNR2MEN1KMT2AMOGAT2 | |
| SCHEMBL4481553 | 0.76 | CNR2 (0.73) | CNR2MOGAT2 | |
| SCHEMBL4481560 | 0.76 | CNR2 (0.73) | CNR2MOGAT2 | |
| SCHEMBL4473004 | 0.76 | CNR2 (0.72) | CNR2MOGAT2 | |
| SCHEMBL2290559 | 0.76 | MEN1 (0.58) | CNR2MEN1KMT2AMOGAT2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966132-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070760-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-21 | — | — | WO | disclosed |