Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 7/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4469485 | 0.89 | CNR2 (0.59) | CNR2LTA4HKDM4EALDH1A1ATM | |
| SCHEMBL4466263 | 0.89 | CNR2 (0.59) | CNR2LTA4HKDM4EALDH1A1ATM | |
| SCHEMBL4466265 | 0.89 | CNR2 (0.59) | CNR2LTA4HKDM4EALDH1A1ATM | |
| SCHEMBL3495379 | 0.83 | LTA4H (0.59) | LTA4HALDH1A1DRD4DRD2DRD3 | |
| SCHEMBL4476032 | 0.82 | CNR2 (0.66) | CNR2LTA4HKDM4EALDH1A1ATM | |
| SCHEMBL4472088 | 0.79 | CNR2 (0.56) | CNR2LTA4HKDM4EALDH1A1ATM | |
| SCHEMBL4476884 | 0.77 | CNR2 (0.58) | CNR2KDM4EALDH1A1ATMCYP1A2 | |
| SCHEMBL4289769 | 0.77 | KDM4E (0.58) | CNR2LTA4HKDM4EALDH1A1ATM | |
| SCHEMBL4475524 | 0.74 | CNR2 (0.87) | CNR2KDM4EALDH1A1ATMBCHE | |
| SCHEMBL2016258 | 0.74 | LTA4H (0.57) | LTA4HALDH1A1LMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966132-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007070760-A2 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-06-21 | — | — | WO | disclosed |