SCHEMBL4649782

SCHEMBL4649782

CC(=O)c1cc(C)c(C)cc1OCC(=O)Nc1ccccc1C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.60
KMT2A Q03164 6/20 0.59
MEN1 O00255 4/20 0.59
CASP3 P42574 1/20 0.59
SENP8 Q96LD8 1/20 0.59
SENP7 Q9BQF6 1/20 0.59
SENP6 Q9GZR1 1/20 0.59
CTDSP1 Q9GZU7 1/20 0.57
NOD2 Q9HC29 1/20 0.57
KDM4E B2RXH2 4/20 0.55
POLB P06746 3/20 0.55
ALDH1A1 P00352 4/20 0.54
HSD17B10 Q99714 2/20 0.53
RAB9A P51151 3/20 0.51
NPC1 O15118 2/20 0.51
LMNA P02545 1/20 0.51
TSHR P16473 2/20 0.50
MAPK10 P53779 2/20 0.50
TRPM4 Q8TD43 2/20 0.50
MAPT P10636 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4650382 0.91 CTDSP1 (0.61) HCAR2KMT2AMEN1CASP3SENP8
SCHEMBL4650577 0.91 HCAR2 (0.56) HCAR2KMT2AMEN1CASP3SENP8
SCHEMBL4697515 0.88 HCAR2 (0.58) HCAR2KMT2AMEN1CASP3SENP8
SCHEMBL4650571 0.87 HCAR2 (0.57) HCAR2KMT2AMEN1CASP3SENP8
SCHEMBL4650476 0.87 HCAR2 (0.59) HCAR2KMT2AMEN1CASP3SENP8
SCHEMBL4650299 0.87 KDM4E (0.64) HCAR2KMT2AMEN1CASP3SENP8
SCHEMBL4649755 0.87 HCAR2 (0.59) HCAR2KMT2AMEN1CASP3SENP8
SCHEMBL4651371 0.87 HCAR2 (0.66) HCAR2KMT2AMEN1CASP3SENP8
SCHEMBL4650573 0.87 HCAR2 (0.56) HCAR2KMT2AMEN1CASP3SENP8
SCHEMBL4651402 0.86 HCAR2 (0.56) HCAR2KMT2AMEN1CASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1966181-A2 ANTHRANILIC ACID DERIVATIVES USEFUL IN TREATING INFECTION WITH HEPATITIS C VIRUS Wyeth (US) 2008-09-10 EP claimed
WO-2008051244-A2 ANTHRANILIC ACID DERIVATIVES USEFUL IN TREATING INFECTION WITH HEPATITIS C VIRUS WYETH (US) 2008-05-02 WO claimed
EP-1966181-A2 ANTHRANILIC ACID DERIVATIVES USEFUL IN TREATING INFECTION WITH HEPATITIS C VIRUS Wyeth (US) 2008-09-10 EP disclosed
WO-2008051244-A2 ANTHRANILIC ACID DERIVATIVES USEFUL IN TREATING INFECTION WITH HEPATITIS C VIRUS WYETH (US) 2008-05-02 WO disclosed