Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | DVL1 | O14640 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4649782 | 0.87 | HCAR2 (0.60) | KDM4EALDH1A1HSD17B10HCAR2MAPT | |
| SCHEMBL4905629 | 0.83 | ALDH1A1 (0.65) | KDM4EALDH1A1HSD17B10HCAR2MAPT | |
| SCHEMBL5024598 | 0.82 | ALDH1A1 (0.65) | KDM4EALDH1A1HSD17B10MAPTRAB9A | |
| SCHEMBL14285634 | 0.81 | MAPT (0.60) | KDM4EALDH1A1HSD17B10HCAR2MAPT | |
| SCHEMBL4912970 | 0.80 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10HCAR2MAPT | |
| SCHEMBL4650382 | 0.78 | CTDSP1 (0.61) | KDM4EALDH1A1HSD17B10HCAR2MAPT | |
| SCHEMBL4650577 | 0.78 | HCAR2 (0.56) | KDM4EALDH1A1HSD17B10HCAR2MAPT | |
| SCHEMBL4912174 | 0.78 | HCAR2 (0.58) | KDM4EALDH1A1HSD17B10HCAR2MAPT | |
| SCHEMBL4912722 | 0.77 | KDM4E (0.65) | KDM4EALDH1A1HSD17B10HCAR2MAPT | |
| SCHEMBL4913830 | 0.76 | ALDH1A1 (0.74) | KDM4EALDH1A1HSD17B10HCAR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966181-A2 | ANTHRANILIC ACID DERIVATIVES USEFUL IN TREATING INFECTION WITH HEPATITIS C VIRUS | Wyeth (US) | 2008-09-10 | — | — | EP | claimed |
| WO-2008051244-A2 | ANTHRANILIC ACID DERIVATIVES USEFUL IN TREATING INFECTION WITH HEPATITIS C VIRUS | WYETH (US) | 2008-05-02 | — | — | WO | claimed |
| EP-1966181-A2 | ANTHRANILIC ACID DERIVATIVES USEFUL IN TREATING INFECTION WITH HEPATITIS C VIRUS | Wyeth (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2008051244-A2 | ANTHRANILIC ACID DERIVATIVES USEFUL IN TREATING INFECTION WITH HEPATITIS C VIRUS | WYETH (US) | 2008-05-02 | — | — | WO | disclosed |