SCHEMBL4649792

SCHEMBL4649792

Cc1cc(O)n(CCO)c(=O)c1C(N)=O

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
GAA P10253 1/20 0.37
HSD17B10 Q99714 1/20 0.36
POLB P06746 2/20 0.36
LMNA P02545 3/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 2/20 0.35
NPSR1 Q6W5P4 1/20 0.34
PIM1 P11309 1/20 0.34
TTK P33981 1/20 0.34
PIM2 Q9P1W9 1/20 0.34
BRD4 O60885 1/20 0.33
BRD9 Q9H8M2 1/20 0.33
CYP1A2 P05177 1/20 0.33
SLC9A1 P19634 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4968505 0.88 POLB (0.36) POLBLMNAMAPTNPSR1BRD4
SCHEMBL11318057 0.88 KDM4E (0.42) KDM4EMEN1KMT2AHSD17B10POLB
SCHEMBL8380174 0.86 KDM4E (0.36) KDM4EMEN1KMT2APOLBLMNA
SCHEMBL9347629 0.85 CNR2 (0.46) KDM4EMEN1KMT2ALMNAALDH1A1
SCHEMBL7883059 0.85 KDM4E (0.42) KDM4EHSD17B10POLBALDH1A1MAPT
SCHEMBL2212267 0.84 KDM4E (0.40) KDM4EKMT2AHSD17B10POLBLMNA
SCHEMBL11428485 0.84 ALDH1A1 (0.36) KDM4EMEN1KMT2AHSD17B10POLB
SCHEMBL11431968 0.82 ALDH1A1 (0.44) KDM4EMEN1KMT2ALMNAALDH1A1
SCHEMBL11424505 0.82 ALDH1A1 (0.44) KDM4EMEN1KMT2ALMNAALDH1A1
SCHEMBL10804739 0.82 POLB (0.33) POLBLMNAMAPTNPSR1BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1000123-B1 USE OF REACTIVE DYES FOR DYEING HAIR BASF SE (DE) 2008-09-10 EP disclosed
EP-1124903-B1 CATIONIC AZO-DYES BASF AG (DE) 2003-06-25 EP disclosed
US-6485527-B1 Use of reactive dyes for dyeing hair BASF AKTIENGESELLSCHAFT (DE) 2002-11-26 US disclosed
EP-0929610-B1 REACTIVE DYES WITH A HETEROCYCLIC ANCHOR DYSTAR TEXTILFARBEN GMBH & CO (DE) 2002-08-28 EP disclosed
US-6346609-B1 DISAZO DYES OR POLYAZO DYES BASF AKTIENGESELLSCHAFT (DE) 2002-02-12 US disclosed
EP-1027387-B1 DOUBLE REACTIVE DYES DYSTAR TEXTILFARBEN GMBH & CO (DE) 2002-02-06 EP disclosed
EP-1124903-A1 CATIONIC AZO-DYES BASF AKTIENGESELLSCHAFT (DE) 2001-08-22 EP disclosed
EP-0955342-B1 Cationic azo dyes derived from aminobenzoic acid BASF AG (DE) 2001-07-11 EP disclosed
US-6197941-B1 TRIAZINE, METALLIZED, AZO, ANTHRAQUINONE, FORMAZAN, PHTHALOCYANINE, AND DIOXAZINE DYES BASF AKTIENGESELLSCHAFT (DE) 2001-03-06 US disclosed
US-6177552-B1 CONTAINING (((VINYLSULFONYL)ALKYLAMINO)ALKYLSULFONYL)PHENYLAZO GROUPS DYSTARTEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 2001-01-23 US disclosed
US-5010180-A Printing, dyeing HOECHST AKTIENGESELLSCHAFT (DE) 1991-04-23 US disclosed
EP-0399411-A1 Water soluble azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1990-11-28 EP disclosed
EP-0391264-A1 Reactive dyes with two or three halogen-N-heterocycles as reactive groups BASF Aktiengesellschaft (DE) 1990-10-10 EP disclosed
EP-0384276-A1 Water soluble azo compounds, method for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-29 EP disclosed
EP-0381133-A1 Water soluble azo compounds, method for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1990-08-08 EP disclosed
EP-0352682-A2 Twice reactive dyes and benzyl compounds as their intermediary products BASF Aktiengesellschaft (DE) 1990-01-31 EP disclosed
EP-0307817-A1 Double reacting dyes and benzyl sulfonyl intermediates BASF Aktiengesellschaft (DE) 1989-03-22 EP disclosed
EP-0078024-B1 WATER-SOLUBLE PYRIDONE AZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1984-09-19 EP disclosed
EP-0078024-A1 Water-soluble pyridone azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1983-05-04 EP disclosed
US-4225491-A REACTIVE DYES FOR COTTON ICI UNITED STATES, INC. (US) 1980-09-30 US disclosed