SCHEMBL464987

SCHEMBL464987

CC(C)(c1ccccc1)C(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 11/20 0.55
ESR2 Q92731 9/20 0.55
CYP3A4 P08684 2/20 0.55
ALDH1A1 P00352 1/20 0.55
AR P10275 2/20 0.41
LMNA P02545 1/20 0.41
TYR P14679 1/20 0.41
HPGD P15428 1/20 0.41
TSHR P16473 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
HTR6 P50406 1/20 0.41
ESRRG P62508 1/20 0.41
SLC6A3 Q01959 1/20 0.41
HSD17B10 Q99714 1/20 0.41
PDCD1 Q15116 1/20 0.41
CD274 Q9NZQ7 1/20 0.41
IDO1 P14902 1/20 0.40
TDO2 P48775 1/20 0.40
NR3C1 P04150 4/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1953133 0.92 ESR1 (0.55) ESR1ESR2CYP3A4ALDH1A1AR
SCHEMBL6550822 0.90 ESR1 (0.54) ESR1ESR2CYP3A4ALDH1A1AR
SCHEMBL980287 0.84 ESR1 (0.55) ESR1ESR2CYP3A4ALDH1A1AR
SCHEMBL1581644 0.81 ESR1 (0.57) ESR1ESR2CYP3A4ALDH1A1AR
SCHEMBL30288156 0.79 ESR1 (0.52) ESR1ESR2CYP3A4ALDH1A1AR
SCHEMBL28598390 0.78 ESR1 (0.50) ESR1ESR2CYP3A4ALDH1A1AR
SCHEMBL15564145 0.76 ESR1 (0.55) ESR1ESR2CYP3A4ALDH1A1AR
SCHEMBL9491108 0.73 RIPK1 (0.34) LMNATSHRSLC6A2SLC6A4SLC6A3
SCHEMBL15349640 0.73 ESR1 (0.50) ESR1ESR2CYP3A4ALDH1A1AR
SCHEMBL28327538 0.73 ESR1 (0.50) ESR1ESR2CYP3A4ALDH1A1AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1360238-B1 DATA STORAGE MEDIA CONTAINING TRANSPARENT POLYCARBONATE BLENDS SABIC INNOVATIVE PLASTICS IP (NL) 2012-01-11 EP disclosed
US-6949279-B2 Data storage media containing transparent polycarbonate blends GENERAL ELECTRIC COMPANY (US) 2005-09-27 US disclosed
US-6936324-B2 Data storage media containing transparent polycarbonate blends GENERAL ELECTRIC COMPANY (US) 2005-08-30 US disclosed
US-6933034-B2 Data storage media containing transparent polycarbonate blends GENERAL ELECTRIC COMPANY (US) 2005-08-23 US disclosed
US-20040024125-A1 Data storage media containing transparent polycarbonate blends SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2004-02-05 US disclosed
US-20030229181-A1 Data storage media containing transparent polycarbonate blends SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2003-12-11 US disclosed
US-20030225214-A1 Data storage media containing transparent polycarbonate blends SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2003-12-04 US disclosed
US-20030225215-A1 Data storage media containing transparent polycarbonate blends HARIHARAN RAMESH (US) 2003-12-04 US disclosed
EP-1360238-A2 DATA STORAGE MEDIA CONTAINING TRANSPARENT POLYCARBONATE BLENDS General Electric Company A Corporation of the State of New York (US) 2003-11-12 EP disclosed
US-6593425-B2 Optical recording media GENERAL ELECTRIC COMPANY 2003-07-15 US disclosed
US-20020035207-A1 Data storage media containing transparent polycarbonate blends SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2002-03-21 US disclosed
WO-2001092419-A2 DATA STORAGE MEDIA CONTAINING TRANSPARENT POLYCARBONATE BLENDS GENERAL ELECTRIC COMPANY (US) 2001-12-06 WO disclosed