Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 2/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL67918 | 0.99 | PPARA (0.39) | PPARAMAPTKDM4ECYP1A2POLB | |
| SCHEMBL68159 | 0.89 | LMNA (0.46) | PPARA | |
| Hydrochloric Acid SCHEMBL69414 | 0.83 | MAOB (0.44) | PPARAMAPTPOLBNR4A2MAOB | |
| SCHEMBL69411 | 0.83 | PPARA (0.40) | PPARAMAPTNR4A2MAOBTP53 | |
| Hydrochloric Acid SCHEMBL70566 | 0.83 | PPARA (0.40) | PPARAMAPTNR4A2MAOBTP53 | |
| Hydrochloric Acid SCHEMBL67921 | 0.82 | PPARA (0.41) | PPARAMAPTNR4A2MAOBTP53 | |
| SCHEMBL69070 | 0.81 | MRGPRX4 (0.46) | PPARAMAPTPOLBNR4A2MAOB | |
| SCHEMBL67655 | 0.81 | MAPT (0.45) | MAPTNR4A2MAOBTP53MRGPRX4 | |
| SCHEMBL69288 | 0.81 | PPARA (0.42) | PPARAMAPTPOLBNR4A2MAOB | |
| SCHEMBL67451 | 0.80 | MAOB (0.41) | PPARAMAPTPOLBNR4A2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963280-A1 | 2 -PHENYLETHYLAMINO DERIVATIVES AS CALCIUM AND/OR SODIUM CHANNEL MODULATORS | Newron Pharmaceuticals S.p.A. (IT) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007071311-A1 | 2 -PHENYLETHYLAMINO DERIVATIVES AS CALCIUM AND/OR SODIUM CHANNEL MODULATORS | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2007-06-28 | — | — | WO | disclosed |