Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL17597299 | 0.98 | PYGM (0.34) | PYGM | |
| Trifluoroacetic Acid SCHEMBL17597661 | 0.89 | KDM1A (0.30) | PYGM | |
| SCHEMBL10554898 | 0.86 | — | — | |
| SCHEMBL29046364 | 0.81 | CHRM3 (0.34) | PYGM | |
| SCHEMBL4827962 | 0.65 | PYGM (0.43) | PYGM | |
| SCHEMBL28599685 | 0.65 | — | — | |
| SCHEMBL934175 | 0.62 | PYGM (0.32) | PYGM | |
| SCHEMBL30608468 | 0.62 | GSK3A (0.43) | — | |
| SCHEMBL30608466 | 0.62 | GSK3A (0.43) | — | |
| SCHEMBL7568266 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4208167-A1 | COMBINATION COMPOSITIONS AND METHODS FOR TREATING CANCER | The Board of Supervisors of Louisiana State University and Agricultural and Mechanical College (US) | 2023-07-12 | — | — | EP | disclosed |
| WO-2022139753-A2 | USE OF BENIDIPINE FOR THE TREATMENT OF EPILEPSY DISEASE | ATATÜRK ÜNİVERSİTESİ BİLİMSEL ARAŞTIRMA PROJELERİ BİRİMİ (TR) | 2022-06-30 | — | — | WO | disclosed |
| EP-3807892-A1 | METHODS FOR LOWERING BLOOD PRESSURE WITH A DIHYDROPYRIDINE-TYPE CALCIUM CHANNEL BLOCKER PHARMACEUTICAL COMPOSITION | AstraZeneca UK Limited (GB) | 2021-04-21 | — | — | EP | disclosed |
| EP-3746446-A1 | PRC2 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2020-12-09 | — | — | EP | disclosed |
| EP-3707143-A1 | NEW ANALOGS AS ANDROGEN RECEPTOR AND GLUCOCORTICOID RECEPTOR MODULATORS | Oncostellae, S.L. (ES) | 2020-09-16 | — | — | EP | disclosed |
| WO-2019152419-A1 | PRC2 INHIBITORS | MIRATI THERAPEUTICS, INC (US) | 2019-08-08 | — | — | WO | disclosed |
| WO-2019078968-A2 | CYCLIC COMPOUNDS AS IMMUNOMODULATING AGENTS | ANGEX PHARMACEUTICAL, INC. (US) | 2019-04-25 | — | — | WO | disclosed |
| CN-108430989-A | The preparation method and intermediate of Isosorbide-5-Nitrae-dihydropyridine -3,5- dicarboxylate derivatives | 山东轩竹医药科技有限公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-104710441-B | Pyridine pentacarbonic acid dipotassium compound and preparation method thereof | 苏州科技学院 | 2017-01-18 | — | — | CN | disclosed |
| EP-3054925-A1 | A STABLE PHARMACEUTICAL COMPOSITION CONTAINING AMLODIPINE AND VALSARTAN | Zentiva K.S. (CZ) | 2016-08-17 | — | — | EP | disclosed |
| WO-2002012235-A1 | 1,4-DIHYDROPYRIDINES AS BRADYKININ ANTAGONISTS | PFIZER PHARMACEUTICALS INC. (JP) | 2002-02-14 | — | — | WO | disclosed |
| WO-1996022772-A1 | METHOD FOR TREATING MULTIPLE SCLEROSIS | ELI LILLY AND COMPANY (US) | 1996-08-01 | — | — | WO | disclosed |
| WO-1996006083-A1 | 2-(PIPERAZINYL-1-CARBONYLMETHYL)-1,4-DIHYDROPYRIDINES AS BRADYKININ ANTAGONISTS | PFIZER PHARMACEUTICALS INC. (JP) | 1996-02-29 | — | — | WO | disclosed |
| US-5342847-A | Antiischetic agents | BAYER AKTIENGESELLSCHAFT (DE) | 1994-08-30 | — | — | US | disclosed |
| CN-1070397-A | Dihydropyridine and method for making and medicinal thereof that the indoles sulphonamide replaces | BAYER AG (DE) | 1993-03-31 | — | — | CN | disclosed |
| EP-0522176-A1 | DIHYDROPYRIDINE COMPOUNDS, AND PROCESS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-01-13 | — | — | EP | disclosed |
| WO-1992013839-A1 | DIHYDROPYRIDINE COMPOUNDS, AND PROCESS FOR THEIR PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-08-20 | — | — | WO | disclosed |
| CN-87102452-A | 1, the derivative of the asymmetric ester of 4-dihydropyridine-3,5-dicarboxylic acid | — | 1987-10-14 | — | — | CN | disclosed |
| CN-87102452-A | 1, the derivative of the asymmetric ester of 4-dihydropyridine-3,5-dicarboxylic acid | — | 1987-10-14 | — | — | CN | disclosed |
| EP-0167371-A2 | Dihydropyridine compounds, their production, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1986-01-08 | — | — | EP | disclosed |