SCHEMBL4649982

SCHEMBL4649982

CC(C)(C)c1cc(C(C)(C)c2ccc(N)c(C(C)(C)C)c2)ccc1N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
MAPT P10636 3/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42
PKM P14618 1/20 0.42
RECQL P46063 1/20 0.42
ESR1 P03372 4/20 0.40
ESR2 Q92731 3/20 0.38
FFAR1 O14842 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36
HPGD P15428 3/20 0.36
HSD17B10 Q99714 2/20 0.36
TSHR P16473 2/20 0.36
AR P10275 2/20 0.36
CYP3A4 P08684 1/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
HTR6 P50406 1/20 0.36
ESRRG P62508 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2201086 0.88 ALDH1A1 (0.54) ALDH1A1MAPTKMT2AMEN1GAA
SCHEMBL29937626 0.83 FFAR4 (0.48) ALDH1A1MAPTKMT2AMEN1GAA
SCHEMBL7194236 0.83 FFAR4 (0.48) ALDH1A1MAPTKMT2AMEN1GAA
SCHEMBL278761 0.83 FFAR1 (0.44) ALDH1A1MAPTKMT2AMEN1GAA
SCHEMBL2754719 0.83 ALDH1A1 (0.44) ALDH1A1MAPTKMT2AMEN1GAA
SCHEMBL9861988 0.79 SMN1; SMN2 (0.41) ALDH1A1MAPTKMT2AMEN1GAA
SCHEMBL14934140 0.79 SMN1; SMN2 (0.41) ALDH1A1MAPTKMT2AMEN1GAA
SCHEMBL687110 0.78 ALDH1A1 (0.46) ALDH1A1MAPTKMT2AMEN1GAA
SCHEMBL30001931 0.78 ALDH1A1 (0.46) ALDH1A1MAPTKMT2AMEN1GAA
Phosphoric Acid SCHEMBL27891991 0.78 ALDH1A1 (0.48) ALDH1A1MAPTKMT2AMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1963390-A1 RIM ELASTOMERS BASED ON ISOCYANURATES OF ISOPHORONE DIISOCYANATE AND PREPOLYMERS THEREOF Bayer MaterialScience LLC (US) 2008-09-03 EP disclosed
WO-2007075329-A1 RIM ELASTOMERS BASED ON ISOCYANURATES OF ISOPHORONE DIISOCYANATE AND PREPOLYMERS THEREOF BAYER MATERIALSCIENCE LLC (US) 2007-07-05 WO disclosed
US-20040220357-A1 Compositions for golf equipment JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2004-11-04 US disclosed