Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2E1 | P05181 | 17/20 | 1.00 |
| ▸ | CYP2C8 | P10632 | 17/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 17/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 17/20 | 1.00 |
| ▸ | CYP2B6 | P20813 | 17/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 17/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 16/20 | 0.84 |
| ▸ | CYP1A2 | P05177 | 15/20 | 0.82 |
| ▸ | BRS3 | P32247 | 1/20 | 0.79 |
| ▸ | NPC1 | O15118 | 2/20 | 0.72 |
| ▸ | RAB9A | P51151 | 2/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.72 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | RELA | Q04206 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4650009 | 0.90 | CYP2E1 (0.81) | CYP2E1CYP2C8CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL29429796 | 0.88 | CYP2E1 (1.00) | CYP2E1CYP2C8CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL6481746 | 0.87 | CYP2E1 (0.76) | CYP2E1CYP2C8CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL2734131 | 0.86 | CYP2E1 (1.00) | CYP2E1CYP2C8CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL15693642 | 0.84 | RAB9A (0.76) | CYP2E1CYP2C8CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL8277910 | 0.84 | CYP2E1 (0.74) | CYP2E1CYP2C8CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL2246151 | 0.84 | RAB9A (1.00) | CYP2E1CYP2C8CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL11686394 | 0.83 | CYP2E1 (1.00) | CYP2E1CYP2C8CYP2D6CYP2C9CYP2B6 | |
| SCHEMBL1064755 | 0.82 | CYP2E1 (0.82) | CYP2E1CYP2C8CYP2D6CYP2C9CYP2B6 | |
| Bromide SCHEMBL1064752 | 0.81 | CYP2E1 (0.80) | CYP2E1CYP2C8CYP2D6CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658099-B1 | COMPOUNDS AND KITS FOR PREPARING IMAGING AGENTS AND METHODS OF IMAGING | GEN ELECTRIC (US) | 2008-09-10 | — | — | EP | disclosed |
| EP-1658099-A1 | COMPOUNDS AND KITS FOR PREPARING IMAGING AGENTS AND METHODS OF IMAGING | General Electric Company (US) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005023317-A1 | COMPOUNDS AND KITS FOR PREPARING IMAGING AGENTS AND METHODS OF IMAGING | GENERAL ELECTRIC COMPANY (US) | 2005-03-17 | — | — | WO | disclosed |
| US-20050049487-A1 | Compounds and kits for preparing imaging agents and methods of imaging | GENERAL ELECTRIC COMPANY | 2005-03-03 | — | — | US | disclosed |